State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China.
J Nat Prod. 2011 Oct 28;74(10):2069-80. doi: 10.1021/np2002918. Epub 2011 Oct 5.
Twelve new arborinane-type triterpenoids (1-12) and four new anthraquinones (13-16), together with 50 known compounds, were isolated from the roots of Rubia yunnanensis. The structures of 1-16 were elucidated by spectroscopic data analysis and chemical methods. All compounds were evaluated for their cytotoxic, antibacterial, and antifungal activities. Rubiyunnanol C (5) is the first example of an arborinane-type triterpenoid with a double bond at C-8-C-9.
从云南茜草的根部分离得到了 12 个新的土槿皮烷型三萜(1-12)和 4 个新的蒽醌(13-16),以及 50 个已知化合物。通过光谱数据分析和化学方法阐明了 1-16 的结构。所有化合物均进行了细胞毒性、抗菌和抗真菌活性评估。Rubiyunnanol C(5)是 C-8-C-9 处具有双键的第一个土槿皮烷型三萜类化合物。