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来自云南茜草的生物活性梓醇型三萜和蒽醌类化合物。

Biologically active arborinane-type triterpenoids and anthraquinones from Rubia yunnanensis.

机构信息

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China.

出版信息

J Nat Prod. 2011 Oct 28;74(10):2069-80. doi: 10.1021/np2002918. Epub 2011 Oct 5.

DOI:10.1021/np2002918
PMID:21973054
Abstract

Twelve new arborinane-type triterpenoids (1-12) and four new anthraquinones (13-16), together with 50 known compounds, were isolated from the roots of Rubia yunnanensis. The structures of 1-16 were elucidated by spectroscopic data analysis and chemical methods. All compounds were evaluated for their cytotoxic, antibacterial, and antifungal activities. Rubiyunnanol C (5) is the first example of an arborinane-type triterpenoid with a double bond at C-8-C-9.

摘要

从云南茜草的根部分离得到了 12 个新的土槿皮烷型三萜(1-12)和 4 个新的蒽醌(13-16),以及 50 个已知化合物。通过光谱数据分析和化学方法阐明了 1-16 的结构。所有化合物均进行了细胞毒性、抗菌和抗真菌活性评估。Rubiyunnanol C(5)是 C-8-C-9 处具有双键的第一个土槿皮烷型三萜类化合物。

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