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单相滑膜肉瘤——一种组织学实体?

Monophasic synovial sarcoma--a histological entity?

作者信息

Mackenzie D H

出版信息

Histopathology. 1977 Mar;1(2):151-7. doi: 10.1111/j.1365-2559.1977.tb01653.x.

Abstract

Consideration is given to the concept of a histologically identifiable monophasic type of synovial sarcoma. It is accepted that a sarcomatous tumour may be encountered where the spindle cells assume a somewhat epithelioid appearance associated with a reticulin pattern unlike that of most other spindle cell sarcomas. The appearance should alert a hsitopathologist to the possibility of a synovial sarcoma and prompt the examination of multiple additional sections in an attempt to find the pathognomonic biphasic pattern. It is not, however, believed that an entire tumour composed of cells of a single type could be identified with certainty as a synovial sarcoma by light microscopy. The term monophasic synovial sarcoma is worthy of retention, but only as a guide towards the establishment of a definite diagnosis by further sampling of the specimen. Other features suggestive of this diagnosis are discussed.

摘要

本文探讨了组织学上可识别的单相型滑膜肉瘤的概念。人们认为,在某些肉瘤性肿瘤中,梭形细胞可能呈现出某种上皮样外观,并伴有与大多数其他梭形细胞肉瘤不同的网状纤维模式。这种表现应提醒组织病理学家注意滑膜肉瘤的可能性,并促使他们检查多个额外切片,试图找到特征性的双相模式。然而,通过光学显微镜,人们并不认为由单一类型细胞组成的整个肿瘤能够被明确诊断为滑膜肉瘤。单相型滑膜肉瘤这一术语值得保留,但仅作为通过对标本进一步取样来确立明确诊断的一个指导。本文还讨论了其他提示该诊断的特征。

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