Bertelli A, Cerrati A, Giovannini L, Mian M, Spaggiari P, Bertelli A A
Department of Pharmacology, Chemotherapy and Medical Toxicology, Milan University, Italy.
Int J Tissue React. 1990;12(6):359-62.
The ethanol-induced increased synthesis of fatty acids in the liver is enhanced by hyperbaric oxygen exposure. Both lipid peroxidation and glutathione depletion are involved in these hepatic alterations. Coenzyme A can intervene in these mechanisms. The administration of CoA prevents hepatic lipid infiltration and the glutathione reduction induced in the rats by ethanol and hyperbaric oxygen exposure.
