University of Malaya, Kuala Lumpur, Malaysia.
Emerg Infect Dis. 2010 Nov;16(11):1783-5. doi: 10.3201/eid1611.100721.
Ancestral sylvatic dengue virus type 1, which was isolated from a monkey in 1972, was isolated from a patient with dengue fever in Malaysia. The virus is neutralized by serum of patients with endemic DENV-1 infection. Rare isolation of this virus suggests a limited spillover infection from an otherwise restricted sylvatic cycle.
1972 年从猴子中分离到的祖先型丛林型 1 型登革病毒,从马来西亚登革热患者中分离到。该病毒被地方性 DENV-1 感染患者的血清中和。这种病毒很少被分离,提示其来自有限的丛林型循环的溢出感染。