Cluster for Physical Activity and Health, Sydney School of Public Health, University of Sydney, Australia.
J Sci Med Sport. 2011 Mar;14(2):149-52. doi: 10.1016/j.jsams.2010.09.002. Epub 2010 Oct 27.
Gestational diabetes mellitus (GDM) complicates approximately 3-11% of pregnancies and increases the risk on prenatal morbidity and later development of type 2 diabetes mellitus. Physical activity and sedentary behaviour are thought to play a role in the development of GDM, independent of overweight and obesity. The aim of this study was to examine the relationships between physical activity, sedentary behaviour and the development of GDM using a population-based prospective cohort study. Data from the youngest (1973-1978) cohort of the Australian Longitudinal Study on Women's Health (n=2913) were used to determine the influences of self-reported physical activity, and sedentary behaviour in 2000 and 2003 on the development of GDM over subsequent three year periods, with adjustment for socio-demographic and lifestyle factors. In this cohort of Australian women, physical activity and sedentary behaviour in 2000 and 2003 were not associated with the development of GDM in the subsequent three years. In adjusted models, odds ratios for the development of GDM were 1.92 (95% CI 1.25-2.96) for overweight women (BMI 25-30 kg/m2) and 3.11 (1.92-5.03) for obese women (BMI≥30 kg/m2) compared with normal weight women. Those with lower education and women born in an Asian country also had higher risk of developing GDM than more highly educated and Australian born women, respectively. In conclusion, pre-pregnancy physical activity and sedentary behaviour appear to be less important in the development of GDM in this cohort than overweight and obesity.
妊娠期糖尿病（GDM）影响约 3-11%的妊娠，增加了产前发病率和日后 2 型糖尿病的风险。体力活动和久坐行为被认为在 GDM 的发生发展中起作用，且与超重和肥胖无关。本研究旨在通过基于人群的前瞻性队列研究，检查体力活动、久坐行为与 GDM 发生之间的关系。本研究使用澳大利亚女性健康纵向研究（1973-1978 年出生队列）中最年轻队列（n=2913）的数据，以确定 2000 年和 2003 年自我报告的体力活动和久坐行为对随后三年内 GDM 发生的影响，并调整了社会人口统计学和生活方式因素。在该队列中，澳大利亚女性在 2000 年和 2003 年的体力活动和久坐行为与随后三年内 GDM 的发生无关。在调整模型中，超重（BMI 25-30 kg/m2）女性和肥胖（BMI≥30 kg/m2）女性发生 GDM 的比值比分别为 1.92（95%CI 1.25-2.96）和 3.11（1.92-5.03），而正常体重女性的比值比为 1。与受教育程度较高和澳大利亚出生的女性相比，受教育程度较低和出生于亚洲国家的女性发生 GDM 的风险更高。总之，与超重和肥胖相比，本队列中妊娠前体力活动和久坐行为在 GDM 的发生发展中似乎并不重要。
