State Key Laboratory of Powder Metallurgy Research Institute, Central South University, 932 Lushan South Road, Changsha 410083, PR China.
Colloids Surf B Biointerfaces. 2011 Feb 1;82(2):490-6. doi: 10.1016/j.colsurfb.2010.10.006. Epub 2010 Oct 30.
Flower-like hydroxyapatite agglomerates formed on the upper side and lower side of an egg-shell membrane were intensively investigated using a uniquely designed crystallizer. First the ion driving force was calculated in theory. In addition the influences of various factors, such as temperature, pH value, and holding time, on the morphology and crystallinity of the agglomerates were studied in detail by means of FESEM, TEM and XRD. It was found that flower-like hydroxyapatite agglomerates with high crystallinity can be produced under higher temperature, larger pH value, and moderated holding time. The information generated is relevant to the formation process of bone.
采用独特设计的结晶器对蛋壳膜上下表面形成的花状羟基磷灰石聚集体进行了深入研究。首先从理论上计算了离子驱动力，此外还通过 FESEM、TEM 和 XRD 详细研究了温度、pH 值和保持时间等各种因素对聚集体形貌和结晶度的影响。结果发现，在较高温度、较大 pH 值和适度的保持时间下，可以得到具有较高结晶度的花状羟基磷灰石聚集体。所得信息与骨形成过程相关。
