Department of Psychology, Emory University, Atlanta, GA, USA.
J Psychiatr Ment Health Nurs. 2010 Nov;17(9):813-20. doi: 10.1111/j.1365-2850.2010.01588.x.
Depression affects more women than men, with a preponderance of cases occurring during prime childbearing years (15-44 years of age). Research shows newborns and infants exposed to maternal antepartum depression, anxiety and stress exhibit pronounced neurobiobehavioral dysregularities. The present study investigated the relationship between maternal psychosocial and biochemical profiles during the antepartum period. Participants were recruited from prenatal registration at a large metropolitan hospital in the southeastern USA--the sample consisted of 59 pregnant women (mean age = 22 years). Structured clinical interviews and maternal self-report were utilized to assess maternal psychosocial distress at mid- (26-28 weeks) and late- (32-34 weeks) gestation. Salivary cortisol levels served as an objective stress measure. The resultant high incidences of maternal depression, anxiety and stress provide evidence of the need for nurses to closely monitor psychosocial and biochemical profiles of all women to thwart the negative effects on the developing human foetus. Clinical nursing implications of the requisite consideration of antepartum maternal psychosocial conditions are discussed.
抑郁症影响的女性多于男性，大多数病例发生在生育高峰期（15-44 岁）。研究表明，暴露于产妇产前抑郁、焦虑和压力下的新生儿和婴儿表现出明显的神经生物行为异常。本研究调查了产前期间产妇社会心理和生化特征之间的关系。参与者是从美国东南部一家大型大都市医院的产前注册中招募的，样本包括 59 名孕妇（平均年龄为 22 岁）。采用结构化临床访谈和产妇自我报告，在妊娠中期（26-28 周）和妊娠晚期（32-34 周）评估产妇的社会心理困扰。唾液皮质醇水平作为客观压力指标。产妇抑郁、焦虑和压力的高发生率表明，护士需要密切监测所有妇女的社会心理和生化特征，以阻止其对发育中人类胎儿的负面影响。讨论了考虑产前产妇社会心理状况的临床护理意义。
