Nemes Attila, Takács Róbert, Gavallér Henriette, Várkonyi Tamás T, Wittmann Tibor, Forster Tamás, Lengyel Csaba
2nd Department of Medicine and Cardiology Center, Medical Faculty, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary.
Clin Physiol Funct Imaging. 2011 Jan;31(1):61-5. doi: 10.1111/j.1475-097X.2010.00980.x. Epub 2010 Oct 12.
There is an increased scientific interest on the evaluation of parameters characterizing aortic elasticity. The current study was designed to compare two characteristics of aortic distensibility: Arteriograph-derived pulse wave velocity (PWV) and augmentation index standardized to 80 per minutes heart rate (AIx80) and aortic elastic properties by echocardiography.
The study comprised 21 adult healthy volunteers. In all cases, systolic and diastolic ascending aortic diameters were recorded during transthoracic echocardiography in M-mode at a level 3 cm above the aortic valve from a parasternal long-axis view. Using forearm blood pressure values, the following aortic elastic properties were calculated: aortic strain, distensibility and stiffness index. All patients were examined by Arteriograph at the same time, as well.
The Arteriograph-derived AIx80 and PWV correlated with aortic strain (R = -0·495, P = 0·023 and R = -0·527, P = 0·014, respectively) and aortic stiffness index (R = 0·454, P = 0·039 and R = 0·608, P = 0·003, respectively). Aortic distensibility did not correlated with AIx80 (R = -0·344, P = 0·127), only with PWV (R = -0·593, P = 0·005, respectively).
Low to moderate correlations could be demonstrated between Arteriograph-derived PWV and aortic elastic properties by echocardiography.
对表征主动脉弹性参数的评估在科学上受到越来越多的关注。本研究旨在比较主动脉扩张性的两个特征：动脉造影衍生的脉搏波速度（PWV）和标准化为每分钟80次心率的增强指数（AIx80），以及通过超声心动图评估的主动脉弹性特性。
本研究纳入21名成年健康志愿者。所有病例均在经胸超声心动图检查时，从胸骨旁长轴视图在主动脉瓣上方3 cm处用M型记录收缩期和舒张期升主动脉直径。利用前臂血压值，计算以下主动脉弹性特性：主动脉应变、扩张性和僵硬度指数。所有患者同时也接受了动脉造影检查。
动脉造影衍生的AIx80和PWV分别与主动脉应变（R = -0·495，P = 0·023和R = -0·527，P = 0·014）以及主动脉僵硬度指数（R = 0·454，P = 0·039和R = 0·608，P = 0·003）相关。主动脉扩张性与AIx80无相关性（R = -0·344，P = 0·127），仅与PWV相关（R = -0·593，P = 0·005）。
动脉造影衍生的PWV与超声心动图评估的主动脉弹性特性之间存在低至中度的相关性。
