Department of Biology, Brandeis University, Waltham, Massachusetts 02454, USA.
Genes Dev. 2010 Nov 1;24(21):2365-82. doi: 10.1101/gad.1953710.
Like other ectotherms, the roundworm Caenorhabditis elegans and the fruit fly Drosophila melanogaster rely on behavioral strategies to stabilize their body temperature. Both animals use specialized sensory neurons to detect small changes in temperature, and the activity of these thermosensors governs the neural circuits that control migration and accumulation at preferred temperatures. Despite these similarities, the underlying molecular, neuronal, and computational mechanisms responsible for thermotaxis are distinct in these organisms. Here, we discuss the role of thermosensation in the development and survival of C. elegans and Drosophila, and review the behavioral strategies, neuronal circuits, and molecular networks responsible for thermotaxis behavior.
像其他变温动物一样，秀丽隐杆线虫和黑腹果蝇依赖于行为策略来稳定体温。这两种动物都使用专门的感觉神经元来检测温度的微小变化，而这些热敏传感器的活性控制着控制迁移和在偏好温度下积累的神经回路。尽管存在这些相似之处，但负责趋热性的分子、神经元和计算机制在这些生物体中是不同的。在这里，我们讨论了热感觉在秀丽隐杆线虫和果蝇的发育和生存中的作用，并回顾了负责趋热行为的行为策略、神经元回路和分子网络。
