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卵巢组织的冷冻保存与移植

Cryopreservation and transplantation of ovarian tissue.

作者信息

Donnez Jacques, Dolmans Marie-Madeleine

机构信息

Department of Gynecology, Université Catholique de Louvain, Brussels, Belgium.

出版信息

Clin Obstet Gynecol. 2010 Dec;53(4):787-96. doi: 10.1097/GRF.0b013e3181f97a55.

DOI:10.1097/GRF.0b013e3181f97a55
PMID:21048445
Abstract

Cryopreservation and autotransplantation of ovarian tissue for fertility preservation is considered an experimental technique. However, in some clinical situations it remains the only option. Eleven pregnancies have been reported worldwide from this procedure. Transplantation of ovarian tissue pieces without a vascular pedicle requires the establishment of a new blood supply that takes 5 days. This leads to a substantial loss of follicles in the graft that may limit the longevity of the graft.

摘要

用于生育力保存的卵巢组织冷冻保存和自体移植被认为是一种实验性技术。然而,在某些临床情况下,它仍然是唯一的选择。全世界已有11例通过该手术成功怀孕的报道。移植没有血管蒂的卵巢组织块需要建立新的血液供应,这需要5天时间。这会导致移植物中大量卵泡损失,可能会限制移植物的存活时间。

相似文献

1
Cryopreservation and transplantation of ovarian tissue.卵巢组织的冷冻保存与移植
Clin Obstet Gynecol. 2010 Dec;53(4):787-96. doi: 10.1097/GRF.0b013e3181f97a55.
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[Cryopreservation of ovarian tissue].
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