Badgaiyan Rajendra D
Department of Psychiatry, University at Buffalo, Buffalo, NY, USA.
Neuroreport. 2010 Dec 29;21(18):1172-6. doi: 10.1097/WNR.0b013e3283410955.
As the role of dopamine in human emotional processing is unclear, we used a dynamic molecular imaging technique to examine whether striatal dopamine is released during processing of negative emotions in healthy volunteers. After volunteers have received an intravenous injection of a dopamine receptor ligand C-raclopride, they were asked to perform a task that elicited negative emotions. During task performance the ligand concentration was measured dynamically using a positron emission tomography camera. Analysis of the data indicated that the task performance is associated with dopamine release in the head of caudate and in the dorsal putamen bilaterally.
由于多巴胺在人类情绪处理中的作用尚不清楚，我们使用动态分子成像技术来检测健康志愿者在处理负面情绪时纹状体多巴胺是否释放。志愿者静脉注射多巴胺受体配体C-雷氯必利后，被要求执行一项引发负面情绪的任务。在任务执行过程中，使用正电子发射断层扫描相机动态测量配体浓度。数据分析表明，任务执行与双侧尾状核头部和背侧壳核中的多巴胺释放有关。
