Sibille Louis, Bouallegue Fayçal Ben, Bourdon Aurélie, Micheau Antoine, Vernhet-Kovacsik Hélène, Mariano-Goulart Denis
Department of Nuclear Medicine, CHRU Lapeyronie, Montpellier, France.
Nucl Med Commun. 2011 Feb;32(2):121-8. doi: 10.1097/MNM.0b013e32834155f1.
Gated blood-pool single-photon emission computed tomography (GBPS) was compared with cardiac magnetic resonance (CMR) for the measurement of left ventricular (LV) and right ventricular (RV) ejection fractions (EF) and volumes [end-diastolic volume (EDV) or end-systolic volume (ESV)] in a mixed population.
Thirty patients (70% men; mean age: 61±14 years) referred for various symptoms or heart diseases, predominantly ischemic, were included. GBPS data were analyzed using segmentation software described earlier based on the watershed algorithm. CMR images were acquired for both ventricles at the same time using a steady-state-free precession sequence and short-axis views. No compensation for papillary muscles was used. LVEF and RVEF and volumes were assessed with GBPS and CMR and were compared.
LVEF and volumes were correlated (P<0.001). The difference in LVEF between GBPS and CMR was not significant (P=0.063). The limits of agreement were close for LVEF (-11 to 15%) and wider for LV volumes (-82 to 11 ml for EDV and -52 to 15 ml for ESV), with higher volume values obtained with CMR (mean differences of 36±24 ml for EDV and 19±17 ml for ESV). The RVEF and volumes assessed by GBPS and CMR were correlated (P<0.001). The difference in RVESV between GBPS or CMR was not significant (P=0.136). The limits of agreement were relatively close for all RV parameters (-15 to 8% for EF; -44 to 22 ml for EDV, and -25 to 21 ml for ESV). In 24 patients without valvulopathy or shunt, the difference between LV stroke volume and RV stroke volume was lower with GBPS than with CMR (9±14 ml and 18±13 ml, respectively, with P=0.027).
GBPS is a simple and widely available technique that can assess both LVEF and RVEF, and volumes with slight differences compared with CMR.
在混合人群中，比较门控心血池单光子发射计算机断层扫描（GBPS）与心脏磁共振成像（CMR）测量左心室（LV）和右心室（RV）射血分数（EF）及容积[舒张末期容积（EDV）或收缩末期容积（ESV）]的情况。
纳入30例因各种症状或心脏病（主要为缺血性心脏病）前来就诊的患者（70%为男性；平均年龄：61±14岁）。使用基于分水岭算法的先前描述的分割软件分析GBPS数据。使用稳态自由进动序列和短轴视图同时采集两个心室的CMR图像。未对乳头肌进行校正。用GBPS和CMR评估左心室射血分数（LVEF）、右心室射血分数（RVEF）及容积，并进行比较。
LVEF与容积相关（P<0.001）。GBPS与CMR之间LVEF的差异无统计学意义（P=0.063）。LVEF的一致性界限较窄（-11%至15%），而左心室容积的一致性界限较宽（EDV为-82至11 ml，ESV为-52至15 ml），CMR测得的容积值更高（EDV的平均差异为36±24 ml，ESV的平均差异为19±17 ml）。GBPS和CMR评估的RVEF与容积相关（P<0.001）。GBPS与CMR之间右心室收缩末期容积（RVESV）的差异无统计学意义（P=0.136）。所有右心室参数的一致性界限相对较窄（EF为-15%至8%；EDV为-44至22 ml，ESV为-25至21 ml）。在24例无瓣膜病或分流的患者中，GBPS测得的左心室每搏量与右心室每搏量之差低于CMR（分别为9±14 ml和18±13 ml，P=0.027）。
GBPS是一种简单且广泛可用的技术，可评估LVEF和RVEF以及容积，与CMR相比存在细微差异。
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