Park Younggeun, Choi Yeonho, Mitra Debkishore, Kang Taewook, Lee Luke P
Appl Phys Lett. 2010 Oct 11;97(15):154101. doi: 10.1063/1.3479052.
Easy trap-and-release of microparticles is necessary to study biological cellular behavior. The hydraulic jump phenomenon inspired us to conceive a microfluidic device for the hydrodynamic trap-and-release of microparticles. A sudden height increase in a microfluidic channel leads to a dramatic decrease in flow velocity, allowing effective trapping of the microparticles by energy conversion. The trapped particles can be released by stronger inertial force based on simply increasing the flow velocity. We present a systematic, numerical study of trap-and-release of the microparticles using multiphase Navier-Stokes equations. Effect of geometry flow velocity, particle diameter, and adhesion force on trap-and-release was studied.
为了研究生物细胞行为，实现微粒的轻松捕获和释放是必要的。水力跃变现象启发我们构思一种用于微粒流体动力捕获和释放的微流控装置。微流控通道中高度的突然增加会导致流速急剧下降，通过能量转换实现对微粒的有效捕获。基于简单地增加流速，利用更强的惯性力可以释放被捕获的粒子。我们使用多相纳维-斯托克斯方程对微粒的捕获和释放进行了系统的数值研究。研究了几何形状、流速、粒径和粘附力对捕获和释放的影响。
