Department of Neurology, Columbia University, New York, NY 10032, USA.
Epilepsy Behav. 2011 Jan;20(1):29-33. doi: 10.1016/j.yebeh.2010.10.005. Epub 2010 Nov 6.
Patients with epilepsy are frequently confronted with complex treatment decisions. Communicating treatment risks is often difficult because patients may have difficulty with basic statistical concepts (i.e., low numeracy) or might misconceive the statistical information based on the way information is presented, a phenomenon known as "framing bias." We assessed numeracy and framing bias in 95 adults with chronic epilepsy and explored cognitive correlates of framing bias. Compared with normal controls, patients with epilepsy had significantly poorer performance on the Numeracy scale (P=0.02), despite a higher level of education than normal controls (P<0.001). Compared with patients with higher numeracy, patients with lower numeracy were significantly more likely to exhibit framing bias. Abstract problem solving performance correlated with the degree of framing bias (r=0.631, P<0.0001), suggesting a relationship between aspects of executive functioning and framing bias. Poor numeracy and susceptibility framing bias place patients with epilepsy at risk for uninformed decisions.
癫痫患者经常面临复杂的治疗决策。由于患者可能难以理解基本的统计概念（即低算数能力），或者可能会根据信息呈现的方式误解统计信息，因此沟通治疗风险通常很困难，这种现象被称为“框架偏差”。我们评估了 95 名慢性癫痫患者的算数能力和框架偏差，并探讨了框架偏差的认知相关性。与正常对照组相比，癫痫患者在算数量表上的表现明显较差（P=0.02），尽管他们的教育水平高于正常对照组（P<0.001）。与算数能力较高的患者相比，算数能力较低的患者更有可能出现框架偏差。抽象问题解决能力与框架偏差程度相关（r=0.631，P<0.0001），这表明执行功能的各个方面与框架偏差之间存在关系。较差的算数能力和易受框架偏差影响使癫痫患者面临不明智决策的风险。
