Peter Jayanthi, David Sarada, Joseph George, Horo Saban, Danda Debashish
Department of Ophthalmology, Schell Eye Hospital, Vellore, India.
Clin Ophthalmol. 2010 Oct 21;4:1173-6. doi: 10.2147/OPTH.S12331.
Takayasu arteritis is a relatively rare inflammatory arteritis that can be associated with ocular manifestations. We report four patients with proven Takayasu arteritis; two patients manifested hypoperfusive ocular manifestations of ocular ischemic syndrome and anterior ischemic optic neuropathy whilst two others had exudative retinal detachment and papilledema as a result of severe hypertension. The ischemic ocular manifestations were a result of hypoperfusion of the ocular structures due to occlusive arteritis of the aortic arch and its branches. The exudative retinal detachment and papilledema were manifestations of severe hypertension due to renal arterial involvement. Patients with Takayasu arteritis should be referred for ophthalmic assessment and screening for hypoperfusive and hypertensive manifestations.
高安动脉炎是一种相对罕见的炎症性动脉炎，可伴有眼部表现。我们报告了4例经证实的高安动脉炎患者；2例表现为眼部缺血综合征和前部缺血性视神经病变的低灌注性眼部表现，另外2例因严重高血压出现渗出性视网膜脱离和视乳头水肿。缺血性眼部表现是由于主动脉弓及其分支的闭塞性动脉炎导致眼部结构灌注不足所致。渗出性视网膜脱离和视乳头水肿是肾动脉受累导致严重高血压的表现。高安动脉炎患者应转诊进行眼科评估，并筛查低灌注和高血压表现。
