Malik Tayyaba Gul, Khalil Muhammad, Ijaz Asad Ullah, Bhatti Muhammad Moeen
Department of Ophthalmology, Lahore Medical and Dental College, Lahore.
Department of Medicine, Lahore Medical and Dental College, Lahore.
J Coll Physicians Surg Pak. 2015 Apr;25 Suppl 1:S47-9.
Ocular Ischemic Syndrome (OIS) is a disorder, which consists of constellation of signs and symptoms secondary to chronic ocular hypoperfusion. We report a case of 35 years old Pakistani female who presented to us with gradual fall of vision in both eyes. On examination, she had bilateral OIS and ischemic optic neuropathy. The patient had past history of transient ischemic attack and facial palsy almost 20 years back. We referred her to physician for the diagnosis of Takayasu arteritis associated with relapsing polychondritis. She was given 60 mg of dexamethasone per day as initial treatment. At her last follow-up after approximately 3 months, she was quite comfortable systemically and her general condition was improved. Unfortunately, her vision did not improve. These two autoimmune diseases are rarely reported together in the same patient in Pakistan. Whether this association is rare or is underdiagnosed still remains to be answered.
眼部缺血综合征（OIS）是一种由慢性眼部灌注不足继发的一系列体征和症状组成的病症。我们报告一例35岁的巴基斯坦女性，她前来就诊时双眼视力逐渐下降。检查发现，她患有双侧OIS和缺血性视神经病变。该患者有近20年前短暂性脑缺血发作和面瘫的病史。我们将她转诊给内科医生以诊断与复发性多软骨炎相关的大动脉炎。初始治疗给予她每天60毫克地塞米松。在大约3个月后的最后一次随访中，她全身状况相当舒适，总体情况有所改善。不幸的是，她的视力没有改善。在巴基斯坦，这两种自身免疫性疾病很少在同一患者中同时被报道。这种关联是罕见还是未被充分诊断仍有待解答。
