Faculty of Health Sciences, Oslo University College, Oslo, Norway.
Osteoporos Int. 2011 Jun;22(6):1863-71. doi: 10.1007/s00198-010-1435-7.
The aim of this randomized controlled trial was to evaluate the effect of a 3-month course of exercises on mobility, balance, disease-specific, and generic health-related quality of life (HRQOL) for women with osteoporosis and a history of vertebral fractures. Our results showed that exercises improved their mobility, balance, and HRQOL.
The aim was to evaluate the effect of a 3-month course of circuit exercises plus a 3-h lesson on how to cope with osteoporosis on mobility, balance, and the HRQOL for postmenopausal women (60-84 years) with osteoporosis and a history of vertebral fracture. Our hypothesis was that a 3-month course would have a significantly positive effect on the women's mobility and balance as well as on their HRQOL.
The participants (89) were randomized to an intervention group (IT) or a control group (CT) and assessed at baseline at 3 months and at 12 months with measurement of maximum walking speed (MWS), Timed Up and GO (TUG), Functional Reach (FR), the Quality of Life Questionnaire issued by the European Foundation for Osteoporosis ('QUALEFFO-41') and the General Health Questionnaire (GHQ-20). The sample size was calculated with reference to walking speed (primary outcome), and the statistical approaches used were Student's t test or the chi-square test.
At 3 months, better results were registered on the primary outcome, MWS as well as TUG, FR, sum score of GHQ-20, and "QUALEFFO-41: mental function" in the IT compared with the CT. At 12 months, those in the IT had a better result on the primary outcome, MWS as well as TUG, "QUALEFFO-41: total score" "QUALEFFO-41: mental function", "QUALEFFO-41: physical function", and "QULEFFO-41: pain" compared with CT.
Circuit exercises will improve mobility and health-related quality of life of elderly women with osteoporosis and a history of vertebral fractures.
本随机对照试验旨在评估为期 3 个月的运动对患有骨质疏松症和椎体骨折病史的女性的活动能力、平衡能力、疾病特异性和一般健康相关生活质量（HRQOL）的影响。我们的结果表明，运动改善了她们的活动能力、平衡能力和 HRQOL。
目的是评估为期 3 个月的循环运动课程加 3 小时关于如何应对骨质疏松症的课程对绝经后妇女（60-84 岁）的活动能力、平衡能力和骨质疏松症和椎体骨折病史的 HRQOL 的影响。我们的假设是，为期 3 个月的课程将对女性的活动能力和平衡能力以及她们的 HRQOL 产生显著的积极影响。
参与者（89 人）被随机分为干预组（IT）或对照组（CT），并在基线、3 个月和 12 个月时进行评估，评估指标包括最大步行速度（MWS）、计时起立行走测试（TUG）、功能性伸展（FR）、欧洲骨质疏松基金会发布的生活质量问卷（'QUALEFFO-41'）和一般健康问卷（GHQ-20）。样本量根据步行速度（主要结局）进行计算，使用的统计方法是学生 t 检验或卡方检验。
在 3 个月时，与 CT 相比，IT 组在主要结局（MWS）以及 TUG、FR、GHQ-20 总分和“QUALEFFO-41：精神功能”方面的结果更好。在 12 个月时，与 CT 相比，IT 组在主要结局（MWS）以及 TUG、“QUALEFFO-41：总分”“QUALEFFO-41：精神功能”“QUALEFFO-41：身体功能”和“QULEFFO-41：疼痛”方面的结果更好。
循环运动将改善患有骨质疏松症和椎体骨折病史的老年女性的活动能力和健康相关生活质量。
