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葡萄牙北部的甲型H1N1流感大流行:秋冬疫情态势如何?

Pandemic influenza A (H1N1) in the North of Portugal: how did the autumn-winter wave behave?

作者信息

Correia A M, Queirós L, Dias J

机构信息

Epidemiological Surveillance Unit, Department of Public Health, Northern Regional Health Administration, Ministry of Health, Porto, Portugal.

出版信息

Rev Port Pneumol. 2010 Nov-Dec;16(6):880-6.

PMID:21067693
Abstract

INTRODUCTION

In April 2009 the Centers for Disease Control and Prevention announced the identification of a novel influenza virus in two patients in California, called influenza A (H1N1) 2009. On 11 June 2009 the Director-General of the World Health Organization declared a pandemic of influenza A (H1N1). In Portugal the first case of pandemic influenza A (H1N1) was reported on 29th April and the Northern Region of the country registered the first cases soon after that.

AIM

This report pretends to give an overview of the characteristics of Autumn/Winter pandemic wave in the North of Portugal.

RESULTS

A total of 64 195 cases of influenza-like illness were registered in public health services in the region between week 40, 2009 and week 4, 2010. The cumulative attack rate of those cases was 17.1/1 000 inhabitants. Most of the cases occurred in females and in the under 20 years. The peak of the Autumn/Winter wave was attained in week 48, but geographic and time distribution of the pandemic was heterogeneous in the region. Hospitalization rate for influenza-like illness cases in the population was higher for the under 10 years and decreased with age. Forty four deaths in pandemic influenza A (H1N1) laboratory-confirmed cases occurred in the region (mortality rate - 1.2/100 000) and the risk of death was lower in younger age groups. The peak of deaths occurred two weeks later than the peak of cases.

CONCLUSION

We can assume that the Autumn/Winter pandemic wave impact was mild in the Northern Region of Portugal. We consider the importance of pursuing and reinforcing influenza surveillance in the region.

摘要

引言

2009年4月,美国疾病控制与预防中心宣布在加利福尼亚州的两名患者身上发现了一种新型流感病毒,即2009年甲型H1N1流感病毒。2009年6月11日,世界卫生组织总干事宣布甲型H1N1流感大流行。在葡萄牙,4月29日报告了首例甲型H1N1流感大流行病例,此后不久该国北部地区也出现了首批病例。

目的

本报告旨在概述葡萄牙北部秋冬大流行波的特征。

结果

2009年第40周(2009年9月27日至10月3日)至2010年第4周(2010年1月24日至30日)期间,该地区公共卫生服务机构共登记了64195例流感样病例。这些病例的累积发病率为17.1/1000居民。大多数病例发生在女性和20岁以下人群中。秋冬波的高峰出现在第48周,但该地区大流行的地理和时间分布并不均匀。10岁以下人群中流感样病例的住院率较高,且随年龄增长而降低。该地区实验室确诊的甲型H1N1流感大流行病例中有44例死亡(死亡率为1.2/100000),且较年轻年龄组的死亡风险较低。死亡高峰比病例高峰晚两周出现。

结论

我们可以认为,秋冬大流行波对葡萄牙北部地区的影响较为轻微。我们认为在该地区继续并加强流感监测非常重要。

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