Department of Pediatrics, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, RS, Brazil.
J Pediatr (Rio J). 2010 Nov-Dec;86(6):531-4. doi: 10.2223/JPED.2037. Epub 2010 Nov 10.
To alert pediatricians to the neurologic consequences of toxocariasis and to describe the first pediatric case of neurotoxocariasis with concomitant cerebral, cerebellar and peripheral nervous system involvement.
We report a case of neurotoxocariasis in a previously healthy 5-year-old boy with unusual symptoms and multi-site involvement of both the central and peripheral nervous system. Differential diagnoses are discussed and the relevant literature is reviewed. Since the early 1950s, fewer than fifty cases have been described, mostly in adult patients.
Although human toxocariasis is one of the most common zoonotic helminth infections, neurotoxocariasis is a rare condition, especially in pediatric patients. Although toxocariasis usually presents as a self-limiting disease with no central nervous system involvement, when it does occur, it can be devastating. Neurotoxocariasis should be added to the differential diagnosis of pediatric patients with unusual neurologic symptoms accompanied by high levels of eosinophils in the cerebrospinal fluid. Early diagnosis and treatment can prevent long-term neurologic sequelae.
提醒儿科医生注意弓蛔虫病的神经系统后果,并描述首例伴有脑、小脑和周围神经系统受累的小儿神经弓蛔虫病病例。
我们报告了一例以前健康的 5 岁男孩患神经弓蛔虫病的病例,该男孩有不常见的症状和中枢及周围神经系统的多部位受累。讨论了鉴别诊断,并回顾了相关文献。自 20 世纪 50 年代初以来,描述的病例不到五十例,大多数发生在成年患者中。
尽管人类弓蛔虫病是最常见的动物源性蠕虫感染之一,但神经弓蛔虫病是一种罕见的疾病,尤其是在儿科患者中。尽管弓蛔虫病通常表现为自限性疾病,无中枢神经系统受累,但当发生时,可能是毁灭性的。对于伴有脑脊液中嗜酸性粒细胞水平升高的不常见神经系统症状的儿科患者,应将神经弓蛔虫病纳入鉴别诊断。早期诊断和治疗可以预防长期的神经系统后遗症。