Ain Shams University, Institute of Psychiatry, Cairo, Egypt.
J Affect Disord. 2011 Apr;130(1-2):180-91. doi: 10.1016/j.jad.2010.10.027. Epub 2010 Nov 11.
There is a growing consensus that persistent cognitive deficits are common in patients with bipolar disorders even when they are euthymic.
The aim was to assess objectively the presence of cognitive deficits in bipolar patients in remission, and to correlate these deficits with the recurrence of the disease.
Cognitive functions (executive function, memory, intelligence, attention and concentration) of a group of euthymic bipolar patients after a single manic episode were compared to cognitive functions of patients who experienced recurrent episodes, both groups were assessed during remission. The results were compared with a control group, using SPSS.
Euthymic bipolar patients assessed after a single manic episode showed impairment in attention, executive functions and total memory score in comparison to healthy control subjects. While they performed better than Euthymic bipolar patients assessed after recurrent bipolar episodes as regards attention and executive function.
Bipolar disorder is associated with attention, memory and executive dysfunction. Attention and executive dysfunction is deteriorated by the recurrence of bipolar episodes.
越来越多的共识认为，即使在双相情感障碍患者处于缓解期时，他们也普遍存在认知缺陷。
旨在客观评估缓解期双相情感障碍患者是否存在认知缺陷，并将这些缺陷与疾病复发相关联。
我们比较了一组单次躁狂发作后处于缓解期的双相情感障碍患者和经历多次发作的患者的认知功能（执行功能、记忆、智力、注意力和集中力），两组均在缓解期进行评估。使用 SPSS 对结果进行了比较。
与健康对照组相比，单次躁狂发作后评估的缓解期双相情感障碍患者在注意力、执行功能和总记忆评分方面存在缺陷。而与经历多次双相情感障碍发作后评估的缓解期双相情感障碍患者相比，他们在注意力和执行功能方面表现更好。
双相情感障碍与注意力、记忆和执行功能障碍有关。双相情感障碍的复发使注意力和执行功能障碍恶化。
