Centre for Research on Drugs & Health Behaviour, Department of Public Health & Policy, London School of Hygiene & Tropical Medicine, London, UK.
Drug Alcohol Depend. 2011 Apr 1;114(2-3):177-84. doi: 10.1016/j.drugalcdep.2010.07.028. Epub 2010 Nov 13.
The prevention of initiation of tobacco, alcohol and drug use is a major societal challenge, for which the existing research literature is generally disappointing. This study aimed to test the effectiveness of adaptation of Motivational Interviewing (MI) for universal prevention purposes, i.e. to prevent initiation of new substance use among non-users, and to reduce risks among existing users.
Cluster randomised trial with 416 students aged 16-19 years old recruited in 12 London Further Education colleges without regard to substance use status. Individualised MI was compared with standard practice classroom-delivered Drug Awareness intervention, both delivered over the course of one lesson. Prevalence, initiation and cessation rates for the 3 target behaviours of cigarette smoking, alcohol consumption and cannabis use, along with reductions in use and harm indicators after both 3 and 12 months were assessed.
This adaptation of MI was not demonstrated to be effective in either intention-to-treat or sub-group analyses for any outcome. Unexpected lower levels of cannabis initiation and prevalence were found in the Drug Awareness control condition.
This particular adaptation of MI is ineffective as a universal drug prevention intervention and does not merit further study.
预防烟草、酒精和药物使用的开始是一个重大的社会挑战，现有研究文献普遍令人失望。本研究旨在测试适应动机访谈（MI）进行普遍性预防的效果，即预防非使用者开始新的物质使用，并降低现有使用者的风险。
在没有考虑物质使用状况的情况下，在伦敦 12 所继续教育学院招募了 416 名 16-19 岁的学生，采用集群随机试验进行。个性化 MI 与标准实践课堂提供的药物意识干预进行比较，两者均在一节课的过程中进行。评估了 3 个目标行为（吸烟、饮酒和大麻使用）的流行率、起始率和终止率，以及在 3 个月和 12 个月后使用和危害指标的减少情况。
在意向治疗或亚组分析中，这种 MI 的适应都没有显示出对任何结果的有效性。在药物意识对照组中，大麻起始和流行率出人意料地较低。
这种特定的 MI 适应作为一种普遍性药物预防干预措施是无效的，不值得进一步研究。
