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MASCP Gator:一个用于可视化拟南芥蛋白质组学数据的聚合门户。

MASCP Gator: an aggregation portal for the visualization of Arabidopsis proteomics data.

机构信息

Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.

出版信息

Plant Physiol. 2011 Jan;155(1):259-70. doi: 10.1104/pp.110.168195. Epub 2010 Nov 12.

Abstract

Proteomics has become a critical tool in the functional understanding of plant processes at the molecular level. Proteomics-based studies have also contributed to the ever-expanding array of data in modern biology, with many generating Web portals and online resources that contain incrementally expanding and updated information. Many of these resources reflect specialist research areas with significant and novel information that is not currently captured by centralized repositories. The Arabidopsis (Arabidopsis thaliana) community is well served by a number of online proteomics resources that hold an abundance of functional information. These sites can be difficult to locate among a multitude of online resources. Furthermore, they can be difficult to navigate in order to identify specific features of interest without significant technical knowledge. Recently, members of the Arabidopsis proteomics community involved in developing many of these resources decided to develop a summary aggregation portal that is capable of retrieving proteomics data from a series of online resources on the fly. The Web portal is known as the MASCP Gator and can be accessed at the following address: http://gator.masc-proteomics.org/. Significantly, proteomics data displayed at this site retrieve information from the data repositories upon each request. This means that information is always up to date and displays the latest data sets. The site also provides hyperlinks back to the source information hosted at each of the curated databases to facilitate more in-depth analysis of the primary data.

摘要

蛋白质组学已成为在分子水平上理解植物过程的功能的重要工具。基于蛋白质组学的研究也为现代生物学中不断扩展的大量数据做出了贡献,其中许多生成了 Web 门户和在线资源,其中包含不断扩展和更新的信息。许多这些资源反映了具有重要和新颖信息的专业研究领域,而这些信息目前并未被集中式存储库捕获。许多在线蛋白质组学资源为拟南芥(Arabidopsis thaliana)社区提供了丰富的功能信息,为其提供了很好的服务。在众多在线资源中,这些站点可能难以找到。此外,如果没有丰富的技术知识,要在这些站点中找到特定的感兴趣的特征并进行导航可能会很困难。最近,参与开发这些资源的拟南芥蛋白质组学社区成员决定开发一个摘要聚合门户,该门户能够从一系列在线资源中即时检索蛋白质组学数据。该 Web 门户称为 MASCP Gator,可在以下地址访问:http://gator.masc-proteomics.org/。重要的是,该站点上显示的蛋白质组学数据在每次请求时都会从数据库中检索信息。这意味着信息始终是最新的,并显示最新的数据集。该站点还提供了指向每个经过策展的数据库中托管的源信息的超链接,以促进对原始数据的更深入分析。

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