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生物库:个性化医疗的基础。

Biobanking: the foundation of personalized medicine.

机构信息

European, Middle Eastern and African Society for Biopreservation and Biobanking (ESBB).

出版信息

Curr Opin Oncol. 2011 Jan;23(1):112-9. doi: 10.1097/CCO.0b013e32834161b8.

DOI:10.1097/CCO.0b013e32834161b8
PMID:21076300
Abstract

PURPOSE OF REVIEW

Biobanking has been identified as a key area for development in order to accelerate the discovery and development of new drugs. This review describes the recent advances in the field of biobanking and biospecimen research, with special reference to tumour banks which are the biobanks of primary interest in oncology.

RECENT FINDINGS

There is a dramatic deficiency of high-quality, well annotated cancer biospecimens. Biospecimen research is a fast developing field that will improve biobanking methodology and biobanking is becoming more professionally organized with increased attention to quality management. Biobank networks are developing rapidly in order to combine and share resources.

SUMMARY

Biobanking services must improve rapidly to serve the needs of personalized medicine and biospecimen research should be encouraged and supported at all levels from project funding to publication of results. Biobanks need to be run to high professional standards and the importance of adequate funding, training and certification must be emphasized. The growing presence of national and international biobank networks will allow biobanks to synergize. The development of a biobanking community will facilitate teamwork to overcome common challenges and enhance communication with multiple stakeholder groups.

摘要

目的综述

生物库已被确定为一个发展的关键领域,以加速新药的发现和开发。本综述描述了生物库和生物样本研究领域的最新进展,特别提到了肿瘤库,它是肿瘤学中主要关注的生物库。

最近的发现

高质量、注释良好的癌症生物样本严重缺乏。生物样本研究是一个快速发展的领域,将改进生物库方法,生物库的组织也越来越专业,对质量管理的重视程度也越来越高。生物库网络正在迅速发展,以便整合和共享资源。

总结

生物库服务必须迅速改进,以满足个性化医疗的需求,应鼓励和支持从项目资助到结果发表的各个层面的生物样本研究。生物库需要按照高标准运行,必须强调充足资金、培训和认证的重要性。国家和国际生物库网络的日益增多将使生物库能够协同工作。生物库社区的发展将促进团队合作,克服共同挑战,并加强与多个利益相关者群体的沟通。

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