Department of Applied Life science, Kon Kuk University, Seoul, South Korea.
Immunopharmacol Immunotoxicol. 2011 Sep;33(3):447-9. doi: 10.3109/08923973.2010.532804. Epub 2010 Nov 16.
The present study evaluated the anti-complement effects from organic solvent extracts of three varieties (Hwanggeumchal Sorghum, Chal Sorghum, and Heuin Sorghum) from Sorghum bicolor in classical pathway complement system. We have evaluated organic solvent extract from Sorghum bicolor varieties with regard to its anti-complement activity. Chal Sorghum ethyl acetate extract showed inhibitory activity against complement system with 50% inhibitory concentrations (IC(50)) values of 38.7 μg/mL. This is the first report of anti-complement activity from Sorghum bicolor varieties.
本研究评估了三种高粱品种（黄高粱、查尔高粱和黑米高粱）有机溶剂提取物对经典途径补体系统的抗补体作用。我们已经评估了高粱品种有机溶剂提取物的抗补体活性。查尔高粱乙酸乙酯提取物对补体系统具有抑制活性，其 50%抑制浓度（IC50）值为 38.7μg/mL。这是高粱品种抗补体活性的首次报道。
