Department of Applied Life Science, Kon Kuk University, Seoul, South Korea.
Hum Exp Toxicol. 2011 Nov;30(11):1865-8. doi: 10.1177/0960327110390066. Epub 2010 Nov 15.
The present study evaluated the antiobesity and lipid-lowering effects from dichloromethane and ethyl acetate extracts of Hwanggeumchal Sorghum varieties on Sorghum bicolor. The Hwanggeumchal Sorghum ethyl acetate extracts significantly reduced the plasma total cholesterol and triglyceride levels significantly when given orally at a dose of 50 and 300 mg/kg/day to the high-fat diet-induced obese rats for 2 weeks. These findings demonstrate the excellent pharmacological potential of Hwanggeumchal Sorghum varieties to prevent obesity.
本研究评估了黄高粱品种的二氯甲烷和乙酸乙酯提取物对高粱的抗肥胖和降血脂作用。黄高粱品种的乙酸乙酯提取物在高脂饮食诱导的肥胖大鼠中，以 50 和 300mg/kg/天的剂量口服给药 2 周，可显著降低血浆总胆固醇和甘油三酯水平。这些发现表明黄高粱品种具有预防肥胖的优异药理学潜力。
