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腭后 Müller 分级与非肥胖亚洲患者阻塞性睡眠呼吸暂停的严重程度相关。腭后 Müller 分级与非肥胖患者的 OSA。

Retropalatal Müller grade is associated with the severity of obstructive sleep apnea in non-obese Asian patients. Retropalatal Müller grade and OSA in non-obese.

机构信息

Department of Otolaryngology, National Taiwan University Hospital Bei-Hu Branch, Taipei, Taiwan.

出版信息

Sleep Breath. 2011 Dec;15(4):799-807. doi: 10.1007/s11325-010-0441-5. Epub 2010 Nov 16.

DOI:10.1007/s11325-010-0441-5
PMID:21080089
Abstract

PURPOSE

The aim of this study was to investigate whether physical evaluations could be used for predicting the presence and severity of obstructive sleep apnea (OSA) in non-obese snoring patients.

METHODS

This is a retrospective study, and a total of 244 non-obese (body mass index, BMI, <27 kg/m(2)) snoring patients (178 men and 66 women; mean age = 43.1 ± 12.1 years) were included. Each patient underwent polysomnography and a thorough physical examination, including flexible nasopharyngoscopy and Müller maneuver. Patients were divided into four groups based on apnea-hypopnea index (AHI) scores: normal (simple snoring), AHI < 5; mild OSA, 5 ≦ AHI < 15; moderate OSA, 15 ≦ AHI < 30; severe OSA, AHI ≧ 30. Logistic regression was used to identify risk factors for OSA severity.

RESULTS

Fifty-nine patients (24%) were simple snorers. The prevalence of sleep apnea (mild, moderate, or severe OSA) for our non-obese snoring patients was 76%. Univariate logistic analyses showed that higher BMI, male gender and retropalatal Müller grades were significantly associated with OSA severity. Multivariate logistic regression analysis identified male gender and retropalatal Müller grade as risk factors for OSA in non-obese snoring patients.

CONCLUSIONS

Physical examination may be useful for studying the upper airway in non-obese snoring patients. Flexible nasopharyngoscopy with Müller maneuver appears to be useful for evaluating the severity of OSA in non-obese patients. Retropalatal Müller grade is highly related to both the presence and severity of OSA, particularly in males.

摘要

目的

本研究旨在探讨体格检查是否可用于预测非肥胖型打鼾患者阻塞性睡眠呼吸暂停(OSA)的存在和严重程度。

方法

这是一项回顾性研究,共纳入 244 例非肥胖(体重指数,BMI,<27kg/m²)打鼾患者(男 178 例,女 66 例;平均年龄=43.1±12.1 岁)。每位患者均接受多导睡眠图检查和全面的体格检查,包括软式鼻咽镜检查和 Müller 动作检查。根据呼吸暂停低通气指数(AHI)评分将患者分为四组:正常(单纯打鼾),AHI<5;轻度 OSA,5≦AHI<15;中度 OSA,15≦AHI<30;重度 OSA,AHI≧30。采用 logistic 回归分析识别 OSA 严重程度的危险因素。

结果

59 例患者(24%)为单纯打鼾者。非肥胖型打鼾患者中睡眠呼吸暂停(轻度、中度或重度 OSA)的患病率为 76%。单因素 logistic 分析显示,较高的 BMI、男性和后鼻咽 Müller 分级与 OSA 严重程度显著相关。多因素 logistic 回归分析表明,男性和后鼻咽 Müller 分级是非肥胖型打鼾患者 OSA 的危险因素。

结论

体格检查可能有助于研究非肥胖型打鼾患者的上气道。软式鼻咽镜检查联合 Müller 动作检查似乎可用于评估非肥胖患者 OSA 的严重程度。后鼻咽 Müller 分级与 OSA 的存在和严重程度高度相关,尤其是在男性中。

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