Department of Surgery, University of Toronto, Toronto, Ontario.
Can J Surg. 2010 Dec;53(6):385-95.
Despite evidence that mechanical bowel preparation (MBP) does not reduce the rate of postoperative complications, many surgeons still use MBP before surgery. We sought to appraise and synthesize the available evidence regarding preoperative bowel preparation in patients undergoing elective colorectal surgery.
We searched MEDLINE, EMBASE and Cochrane Databases to identify randomized controlled trials (RCTs) comparing patients who received a bowel preparation with those who did not. Two authors reviewed the abstracts to identify articles for critical appraisal. We used the methods of the United States Preventive Services Task Force to grade study quality and level of evidence, as well as formulate the final recommendations. Outcomes assessed included postoperative infectious complications, such as anastomotic dehiscence and superficial surgical site infections.
Our review identified 14 RCTs and 8 meta-analyses. Based on the quality and content of these original manuscripts, we formulated 6 recommendations for various aspects of bowel preparation in patients undergoing elective colorectal surgery.
Taking into account the lack of difference in postoperative infectious complication rates when MBP is omitted and the adverse effects of MBP, we believe that, based on the literature, MBP before surgery should be omitted.
尽管有证据表明机械肠道准备(MBP)并不能降低术后并发症的发生率,但许多外科医生仍在手术前使用 MBP。我们旨在评估和综合现有的关于择期结直肠手术患者术前肠道准备的证据。
我们检索了 MEDLINE、EMBASE 和 Cochrane 数据库,以确定比较接受肠道准备和未接受肠道准备的患者的随机对照试验(RCT)。两位作者审查了摘要以确定进行批判性评价的文章。我们使用美国预防服务工作组的方法对研究质量和证据水平进行分级,并制定最终建议。评估的结果包括术后感染性并发症,如吻合口裂开和浅表手术部位感染。
我们的综述确定了 14 项 RCT 和 8 项荟萃分析。基于这些原始手稿的质量和内容,我们针对择期结直肠手术患者的肠道准备的各个方面制定了 6 项建议。
考虑到省略 MBP 后术后感染性并发症发生率没有差异,以及 MBP 的不良反应,我们认为,根据文献,术前 MBP 应该被省略。