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经典杂交技术在远端弓部动脉瘤中的应用:向 Zone0 解决方案迈进。

Classic hybrid evolving approach to distal arch aneurysms: toward the zone zero solution.

机构信息

Hospital of the University of Pennsylvania, Department of Surgery, Philadelphia, PA, USA.

出版信息

J Thorac Cardiovasc Surg. 2010 Dec;140(6 Suppl):S77-80; discussion S86-91. doi: 10.1016/j.jtcvs.2010.07.031.

Abstract

BACKGROUND

A combined open surgical and endovascular approach to managing aneurysms of the distal aortic arch (hybrid arch repair) is evolving as a viable treatment option. Our aim is to describe a treatment strategy in high-risk patients and report the technical and clinical success of the hybrid approach to aneurysms involving the distal aortic arch.

METHODS

From July 2005 until December 2009, 27 consecutive patients with aneurysms of the distal aortic arch were treated via a hybrid arch repair. Of this group, 23 patients underwent aortic arch debranching and revascularization before endovascular stent deployment in the ascending aorta (type I). Four patients required ascending aortic and transverse arch replacement before stent graft deployment (type II).

RESULTS

A stent graft was successfully deployed in 100% of patients after aortic arch vessel debranching via median sternotomy. The mean age of the patients was 71 ± 7.5 years. The average cardiopulmonary bypass time was 199 ± 84 minutes with an average crossclamp time of 57 ± 53 minutes. Deep hypothermic circulatory arrest was required in 4 patients (all type II). The average length of stay was 17.2 ± 14 days. The complications included stroke in 3 (11%) patients, permanent paralysis in 2 (7%), and perioperative death in 3 (11%) patients.

CONCLUSIONS

Early results of type I and II hybrid arch repair, in this cohort of patients with mutiple comorbid risk factors, are acceptable and even encouraging. This evolving approach to aneurysms involving the aortic arch may extend the indications for use of endovascular prostheses in the treatment of patients with complex aortic arch disease.

摘要

背景

联合开放手术和血管内治疗方法治疗远端主动脉弓动脉瘤(杂交弓修复)正在发展成为一种可行的治疗选择。我们的目的是描述一种高危患者的治疗策略,并报告涉及远端主动脉弓动脉瘤的杂交方法的技术和临床成功。

方法

从 2005 年 7 月至 2009 年 12 月,27 例连续的远端主动脉弓动脉瘤患者通过杂交弓修复进行治疗。在这组患者中,23 例患者在升主动脉内支架置入前进行主动脉弓分支血管重建(I 型)。4 例患者需要在支架置入前进行升主动脉和横弓置换(II 型)。

结果

在经正中胸骨切开术进行主动脉弓血管分支重建后,100%的患者成功地放置了支架移植物。患者的平均年龄为 71±7.5 岁。体外循环时间平均为 199±84 分钟,平均夹闭时间为 57±53 分钟。4 例患者(均为 II 型)需要深低温停循环。平均住院时间为 17.2±14 天。并发症包括 3 例(11%)患者发生脑卒中,2 例(7%)患者发生永久性瘫痪,3 例(11%)患者围手术期死亡。

结论

在这组患有多种合并症高危因素的患者中,I 型和 II 型杂交弓修复的早期结果是可以接受的,甚至是令人鼓舞的。这种涉及主动脉弓的动脉瘤的新兴治疗方法可能会扩大血管内假体在治疗复杂主动脉弓疾病患者中的应用范围。

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