Key Laboratory of Chemical Safety and Health, and National Institute of Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, 7 Panjiayuan nanli Road, Chaoyang District, Beijing 100021, China.
Environ Pollut. 2011 Feb;159(2):524-31. doi: 10.1016/j.envpol.2010.10.014. Epub 2010 Nov 19.
The occurrence of persistent organochlorine pesticides (OCPs) in breast milk samples collected from mothers from twelve provinces in mainland China was investigated. Dichlorodiphenyltrichloroethanes (DDTs) were the most prevalent agent, followed by HCHs and HCB, whereas levels of chlordane compounds, drins and mirex were lower. The relatively lower DDE/DDT ratio in the Fujian rural area suggested more recent exposure to DDT than in other areas. The mean level of DDTs in breast milk from the southern China was higher than those from northern China (p < 0.05). A positive correlation was observed between concentration of DDTs in human milk and consumption of animal-origin food, suggesting that this parameter could play an important part in influencing OCPs burdens in lactating women. The mean estimated daily intakes of different OCPs for breastfed infants were lower than the tolerable daily intake.
本研究调查了中国大陆 12 个省份母亲的母乳样本中持久性有机氯农药（OCPs）的存在情况。二氯二苯三氯乙烷（DDTs）是最常见的农药，其次是六氯环己烷（HCHs）和六氯苯（HCB），而氯丹化合物、滴滴涕和灭蚁灵的水平较低。福建农村地区 DDE/DDT 比值相对较低，表明与其他地区相比，最近接触滴滴涕的情况更为普遍。来自中国南方的母乳中 DDTs 的平均水平高于北方（p < 0.05）。人体乳中滴滴涕浓度与动物源性食品的消费呈正相关，表明该参数可能在影响哺乳期妇女的 OCPs 负担方面发挥重要作用。母乳喂养婴儿对不同 OCPs 的日均估计摄入量低于可耐受日摄入量。
