UCL-Institute of Child Health, Great Ormond Street Hospital, London & National Centre for Young people with Epilepsy, Lingfield, UK.
Seizure. 2010 Dec;19(10):671-4. doi: 10.1016/j.seizure.2010.10.021. Epub 2010 Nov 19.
The ketogenic diet has been used for the treatment of epilepsy in childhood for almost 100 years. Although initial use was wide, the advent of antiepileptic drugs led to reduced utilisation. However, an apparently 'forgotten treatment' gained further popularity in the early 1990s when significant individuals gained benefit. This aside, although there are many open label trials to suggest benefit can be gained in children with drug resistant epilepsy it is only recently that definitive evidence from randomised controlled trials has become available. There continues to be a constant struggle with the demand for the resources required, and therefore availability and apparent management choice is limited.
生酮饮食法用于治疗儿童癫痫已有近 100 年的历史。尽管最初的应用很广泛，但抗癫痫药物的出现导致了其应用的减少。然而，一种明显的“被遗忘的治疗方法”在 20 世纪 90 年代再次流行起来，当时一些重要的人从中受益。除此之外，尽管有许多开放标签试验表明生酮饮食对耐药性癫痫儿童有益，但直到最近才有随机对照试验的明确证据。对于所需资源的需求仍然存在持续的争议，因此，其可用性和明显的管理选择是有限的。
