Department of Biology, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, PR China.
Phytochemistry. 2011 Jan;72(1):21-6. doi: 10.1016/j.phytochem.2010.10.015. Epub 2010 Nov 19.
Tripterygium wilfordii Hook.f., known as Leigongteng (Thunder God Vine) in traditional Chinese medicine, has attracted much attention for its applications in relieving autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus, and for treating cancer. Molecular analyses of the ITS and 5S rDNA sequences indicate that T. hypoglaucum and T. doianum are not distinct from T. wilfordii, while T. regelii should be recognized as a separate species. The results also demonstrate potential value of rDNA sequence data in forensic detection of adulterants derived from Celastrus angulatus in commercial samples of Leigongteng.
雷公藤(Tripterygium wilfordii Hook.f.),又称雷公藤,在中国传统医学中应用广泛,可缓解类风湿性关节炎和系统性红斑狼疮等自身免疫性疾病,并具有抗癌作用。ITS 和 5S rDNA 序列的分子分析表明,T. hypoglaucum 和 T. doianum 与 T. wilfordii 没有明显区别,而 T. regelii 应被视为一个独立的物种。研究结果还表明,rDNA 序列数据在法医学检测雷公藤商业样品中来源于南蛇藤(Celastrus angulatus)的掺杂物方面具有潜在价值。