Department of Psychology, The Ohio State University, 225 Psychology Building, 1835 Neil Avenue, Columbus, OH 43210, USA.
Immunol Allergy Clin North Am. 2011 Feb;31(1):81-93. doi: 10.1016/j.iac.2010.09.010.
Converging and replicated evidence indicates that psychological stress can modulate wound-healing processes. This article reviews the methods and findings of experimental models of wound healing. Psychological stress can have a substantial and clinically relevant impact on wound repair. Physiologic stress responses can directly influence wound-healing processes. Furthermore, psychological stress can indirectly modulate the repair process by promoting the adoption of health-damaging behaviors. Translational work is needed to develop innovative treatments able to attenuate stress-induced delays in wound healing.
越来越多的证据表明，心理压力可以调节伤口愈合过程。本文综述了伤口愈合实验模型的方法和结果。心理压力对伤口修复有实质性的、临床相关的影响。生理应激反应可以直接影响伤口愈合过程。此外，心理压力还可以通过促进有害健康行为的发生来间接调节修复过程。需要开展转化研究来开发创新疗法，以减轻压力引起的伤口愈合延迟。
