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女性下尿路感染。

Urinary tract infections in women.

机构信息

Department of Urology, Northwestern University, Feinberg School of Medicine, 303 East Chicago Avenue, Tarry 16-703, Chicago, IL 60611-3008, USA.

出版信息

Med Clin North Am. 2011 Jan;95(1):27-41. doi: 10.1016/j.mcna.2010.08.023.

Abstract

Urinary tract infection (UTI) is the most common extraintestinal infectious disease entity in women worldwide, and perhaps one of the most formidable challenges in clinical practice given its high prevalence, frequent recurrence, and myriad associated morbidities in the setting of rapidly evolving antimicrobial resistance. Achieving timely symptom relief and infection control and preventing morbidity, growth of resistant organisms, and recurrent infection are often difficult. This article reviews epidemiology and pathogenesis of urinary tract infection in women; characterizes common patterns of infection, clinical red flags, and appropriate laboratory testing and imaging; explores emerging patterns of antimicrobial resistance; and reviews the updated guidelines for the treatment of uncomplicated UTI in women.

摘要

尿路感染(UTI)是全球女性中最常见的肠道外感染性疾病实体,由于其高发率、频繁复发以及在抗菌药物耐药性迅速发展的情况下存在多种相关并发症,这可能是临床实践中最具挑战性的问题之一。实现及时缓解症状和控制感染,预防发病、耐药菌生长和反复感染通常较为困难。本文综述了女性尿路感染的流行病学和发病机制;描述了常见的感染模式、临床警示征象以及适当的实验室检查和影像学检查;探讨了抗菌药物耐药性的新出现模式;并回顾了女性单纯性尿路感染治疗的更新指南。

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