结直肠癌孤立性胫骨骨转移的治疗

Chalkidou Anastasia S, Boutis Anastasios L, Padelis Panagiotis

Clinical Oncology Department, Theagenion Cancer Hospital of Thessaloniki, Thessaloniki, Greece.

Case Rep Gastroenterol. 2009 Nov 21;3(3):354-359. doi: 10.1159/000239626.

The onset of osseous metastases during the course of colorectal cancer is not common. When they appear they are usually combined with visceral metastases to the liver, lungs and brain. In our report we refer to the case of a 78-year-old patient who presented a solitary bone metastasis from rectal carcinoma in the middle of his right tibia. A year before he had been operated for a Dukes stage B1 adenocarcinoma of the rectum. The rest of the check was negative for other metastases. He received external radiotherapy and capecitabine with bisphosphonates as palliative treatment. 19 months after the original diagnosis of bone metastasis the patient has stable disease.

在结直肠癌病程中发生骨转移并不常见。当出现骨转移时，通常还伴有肝、肺和脑等内脏转移。在我们的报告中，提及了一名78岁患者的病例，该患者右胫骨中部出现了来自直肠癌的孤立性骨转移。一年前，他因直肠 Dukes B1期腺癌接受了手术治疗。其余检查未发现其他转移。他接受了外照射放疗以及以双膦酸盐类药物辅助的卡培他滨进行姑息治疗。在最初诊断骨转移19个月后，该患者病情稳定。