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Multiple functionalities of polyelectrolyte multilayer films: new biomedical applications.聚电解质多层膜的多种功能：新的生物医学应用。
Adv Mater. 2010 Jan 26;22(4):441-67. doi: 10.1002/adma.200901327.
2
Multilayered Films Fabricated from Combinations of Degradable Polyamines: Tunable Erosion and Release of Anionic Polyelectrolytes.由可降解多胺组合制成的多层膜：阴离子聚电解质的可调降解与释放
Macromolecules. 2006 Jan 26;39(26):8928-8935. doi: 10.1021/ma061815g.
3
Release of a model protein from biodegradable self assembled films for surface delivery applications.用于表面递送应用的可生物降解自组装膜中模型蛋白的释放。
J Control Release. 2008 Nov 12;131(3):228-34. doi: 10.1016/j.jconrel.2008.07.032. Epub 2008 Jul 30.
4
Polyelectrolyte multilayers for tunable release of antibiotics.用于抗生素可调释的聚电解质多层膜。
Biomacromolecules. 2008 Jun;9(6):1660-8. doi: 10.1021/bm800185h. Epub 2008 May 14.
5
Multilayered polyelectrolyte assemblies as platforms for the delivery of DNA and other nucleic acid-based therapeutics.多层聚电解质组装体作为用于递送DNA和其他基于核酸的治疗剂的平台。
Adv Drug Deliv Rev. 2008 Jun 10;60(9):979-99. doi: 10.1016/j.addr.2008.02.010. Epub 2008 Mar 4.
6
Multilayered films fabricated from plasmid DNA and a side-chain functionalized poly(beta-amino ester): surface-type erosion and sequential release of multiple plasmid constructs from surfaces.由质粒DNA和侧链功能化聚（β-氨基酯）制备的多层膜：表面型侵蚀及多种质粒构建体从表面的顺序释放
Langmuir. 2007 Oct 23;23(22):11139-46. doi: 10.1021/la702021s. Epub 2007 Sep 22.
7
Release mechanisms for polyelectrolyte capsules.聚电解质胶囊的释放机制。
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8
Nanometer-scale decomposition of ultrathin multilayered polyelectrolyte films.超薄多层聚电解质薄膜的纳米级分解
Langmuir. 2007 Feb 27;23(5):2273-6. doi: 10.1021/la0624182.
9
Release of plasmid DNA from intravascular stents coated with ultrathin multilayered polyelectrolyte films.从涂覆有超薄多层聚电解质薄膜的血管内支架中释放质粒DNA。
Biomacromolecules. 2006 Sep;7(9):2483-91. doi: 10.1021/bm0604808.
10
Preparation of ultrathin self-standing polyelectrolyte multilayer membranes at physiological conditions using pH-responsive film segments as sacrificial layers.利用pH响应性膜段作为牺牲层在生理条件下制备超薄自支撑聚电解质多层膜。
Nano Lett. 2006 Apr;6(4):592-8. doi: 10.1021/nl0515504.

聚电解质多层膜中质粒 DNA 的快速释放：一种弱聚酸法。

Rapid release of plasmid DNA from polyelectrolyte multilayers: a weak poly(acid) approach.

机构信息

Department of Chemical and Biological Engineering, University of Wisconsin-Madison, 1415 Engineering Drive, Madison, WI 53706, USA.

出版信息

Chem Commun (Camb). 2011 Jan 7;47(1):550-2. doi: 10.1039/c0cc02926b. Epub 2010 Nov 23.

DOI:10.1039/c0cc02926b
PMID:21103586
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3564967/
Abstract

We demonstrate an approach to the assembly of DNA-containing polyelectrolyte multilayers that can be used to promote rapid release of DNA from surfaces. The approach is based on layer-by-layer incorporation of poly(acrylic acid) to promote rapid erosion in physiologically relevant media.

摘要

我们展示了一种用于组装含 DNA 的聚电解质多层的方法，该方法可用于促进 DNA 从表面的快速释放。该方法基于聚（丙烯酸）的逐层掺入以在生理相关介质中促进快速侵蚀。