Department of Occupational and Environmental Medicine, Bispebjerg University Hospital, 2400 Copenhagen NV, Denmark.
Scand J Work Environ Health. 2011 Jul;37(4):332-40. doi: 10.5271/sjweh.3135. Epub 2010 Nov 23.
To test the hypothesis that the association between levels of mould in floor dust and prevalence of potentially building-related symptoms may depend on the type of ventilation.
This stratified cross-sectional study is part of the Danish moulds in buildings program (DAMIB), including 503 adolescent schoolboys aged 13-17 years at 15 schools. Besides assessing symptom prevalences in questionnaires, we measured numerous potential risk factors in the school buildings.
Stratifying on type of ventilation (natural, exhaust only, or full mechanical ventilation system), the negative effect of high levels of mould in floor dust was more pronounced in rooms with mechanical ventilation system. With a variable combining high level of moulds in floor dust with type of ventilation in the classroom, a significantly increased risk was found for all symptoms in the mechanically ventilated classrooms with high mould concentrations. In multiple logistic regression models, significant odds ratios (OR) ranged from 3.9 [95% confidence interval (95% CI) 1.5-10.1] (nasal congestion) to 17.0 (95% CI 2.1-138) (dizziness).
The combined effect of moulds in dust and ventilation form might be a result of the higher air flow keeping the dust in the breathing zone for a longer time, thereby increasing the exposure for the occupants of the classrooms. It is important in future indoor air research also to focus on the combination effects of risk factors, including the type of ventilation.
检验假设,即地板灰尘中霉菌水平与潜在建筑相关症状的患病率之间的关联可能取决于通风类型。
这是一项分层的横断面研究,是丹麦建筑物霉菌项目(DAMIB)的一部分,共纳入了 15 所学校的 503 名 13-17 岁的青少年男生。除了在问卷中评估症状的患病率外,我们还在学校建筑中测量了许多潜在的风险因素。
根据通风类型(自然通风、仅排气通风或全机械通风系统)进行分层,地板灰尘中高水平霉菌的负面影响在机械通风系统的房间中更为明显。在教室中结合地板灰尘中高水平霉菌和通风类型的变量中,发现机械通风教室中霉菌浓度高的所有症状的风险显著增加。在多项逻辑回归模型中,显著的优势比(OR)范围从 3.9(95%置信区间[95%CI] 1.5-10.1)(鼻塞)到 17.0(95%CI 2.1-138)(头晕)。
灰尘中的霉菌和通风形式的联合效应可能是由于较高的气流使灰尘在呼吸区停留更长时间,从而增加了教室使用者的暴露风险。在未来的室内空气研究中,也很重要的是要关注包括通风类型在内的风险因素的组合效应。