Gazyağci Serkal, Azkur Ahmet Kursat, Cağlayan Osman
Department of Internal Medicine, School of Veterinary Medicine, Kirikkale University, 71451, Kirikkale, Turkey.
Trop Anim Health Prod. 2011 Mar;43(3):553-6. doi: 10.1007/s11250-010-9754-4. Epub 2010 Nov 21.
In this study, we investigated the changes occurring in the activities of determining the biochemical and hematological parameters in persistently infected sheep with border disease virus (BDV) and control sheep. While cholesterol, aspartate aminotransferase, lactate dehydrogenase, high-density lipoprotein, and glucose parameters were found to be statistically different between control and BDV positive groups (p<0.01), total protein, alkaline phosphotase, creatine kinase, amylase, glucose, and high-density lipoprotein were found to be statistically different between control and persistently infected group (p<0.01). Interestingly, all groups were shown only mean corpuscular volume parameter was different (p<0.01). It was found that cholesterol, aspartate aminotransferase, amylase, high-density lipoprotein, and low-density lipoprotein parameters were different between PI and infected sheep (p<0.01). It was speculated that BDV might effect also the expression of low-density lipoprotein receptor and determination of the changes in BD and its clinical importance might contribute to the veterinarians and scientists studying in this area.
在本研究中，我们调查了持续感染边界病病毒（BDV）的绵羊和对照绵羊在生化和血液学参数测定活动中发生的变化。虽然发现对照和BDV阳性组之间的胆固醇、天冬氨酸转氨酶、乳酸脱氢酶、高密度脂蛋白和葡萄糖参数存在统计学差异（p<0.01），但发现对照和持续感染组之间的总蛋白、碱性磷酸酶、肌酸激酶、淀粉酶、葡萄糖和高密度脂蛋白存在统计学差异（p<0.01）。有趣的是，所有组仅显示平均红细胞体积参数不同（p<0.01）。发现PI绵羊和感染绵羊之间的胆固醇、天冬氨酸转氨酶、淀粉酶、高密度脂蛋白和低密度脂蛋白参数不同（p<0.01）。据推测，BDV可能也会影响低密度脂蛋白受体的表达，确定BD的变化及其临床重要性可能有助于该领域的兽医和科学家。
