癌症治疗中的无机纳米颗粒。
Inorganic nanoparticles in cancer therapy.
机构信息
Department of Biochemistry and Molecular Biology College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA.
出版信息
Pharm Res. 2011 Feb;28(2):237-59. doi: 10.1007/s11095-010-0318-0. Epub 2010 Nov 23.
Abstract
Nanotechnology is an evolving field with enormous potential for biomedical applications. The growing interest to use inorganic nanoparticles in medicine is due to the unique size- and shape-dependent optoelectronic properties. Herein, we will focus on gold, silver and platinum nanoparticles, discussing recent developments for therapeutic applications with regard to cancer in terms of nanoparticles being used as a delivery vehicle as well as therapeutic agents. We will also discuss some of the key challenges to be addressed in future studies.
摘要
纳米技术是一个具有巨大生物医学应用潜力的不断发展的领域。人们越来越有兴趣将无机纳米粒子应用于医学领域，这是由于其独特的尺寸和形状依赖的光电特性。在这里，我们将重点讨论金、银和铂纳米粒子，讨论近年来在癌症治疗应用方面的进展，包括将纳米粒子用作递送载体和治疗剂。我们还将讨论未来研究中需要解决的一些关键挑战。
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