Division of Nutrition Research Coordination, National Institutes of Health, Bethesda, MD 20892, USA.
J Nutr. 2011 Jan;141(1):1-3. doi: 10.3945/jn.110.134106. Epub 2010 Nov 24.
Over one-half of U.S. adults use dietary supplements, so federally supported research into the safety and effectiveness of these compounds is important for the health of many Americans. Data collected in the Computer Access to Research on Dietary Supplements database, which compiles federally sponsored dietary supplement-related research, are useful to scientists in determining the type of dietary supplement research that federal agencies are currently funding and where research gaps exist. This article describes the dietary supplement-related research funded by the NIH and the USDA. Between fiscal years 1999 and 2007, the number of research projects and funding for dietary supplement research more than doubled. During that period, NIH funded 6748 dietary supplement-related projects at a cost of $1.9 billion and the USDA funded 2258 projects at a cost of $347 million. The top funded dietary supplement ingredient categories were vitamins and minerals, botanicals, phytochemicals, and fatty acids. Cancer was by far the most frequent health outcome in dietary supplement research funding, nearly double the next closest health outcome category. Other health outcomes with the greatest funding were cellular and molecular mechanisms, cardiovascular health, women's reproductive health, and immune function. The greatest number of dietary supplement research projects are funded by the NIH National Cancer Institute, the NIH National Center for Complementary and Alternative Medicine, the NIH Office of Dietary Supplements, and the USDA Agricultural Research Service.
超过一半的美国成年人使用膳食补充剂，因此，联邦政府支持对这些化合物的安全性和有效性进行研究，这对许多美国人的健康至关重要。计算机访问膳食补充剂研究数据库（该数据库汇编了联邦赞助的与膳食补充剂相关的研究）中收集的数据，可帮助科学家确定联邦机构目前正在资助的膳食补充剂研究类型以及存在研究空白的地方。本文描述了 NIH 和 USDA 资助的与膳食补充剂相关的研究。在 1999 年至 2007 财年期间，膳食补充剂研究的研究项目和资金增加了一倍多。在此期间，NIH 资助了 6748 个与膳食补充剂相关的项目，耗资 19 亿美元，而 USDA 资助了 2258 个项目，耗资 3.47 亿美元。资金最多的膳食补充剂成分类别是维生素和矿物质、植物药、植物化学物质和脂肪酸。癌症是迄今为止膳食补充剂研究资金中最常见的健康结果，几乎是下一个最接近的健康结果类别的两倍。其他具有最大资金投入的健康结果是细胞和分子机制、心血管健康、女性生殖健康和免疫功能。NIH 国家癌症研究所、NIH 国家补充和替代医学中心、NIH 膳食补充剂办公室和 USDA 农业研究局资助了最多的膳食补充剂研究项目。
