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本文引用的文献

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Herb-drug interactions: focus on pharmacokinetics.草药-药物相互作用:聚焦于药代动力学。
CNS Spectr. 2001 Oct;6(10):827-32. doi: 10.1017/s1092852900001644.
2
St John's wort: a systematic review of adverse effects and drug interactions for the consultation psychiatrist.圣约翰草:为会诊精神科医生提供的关于不良反应和药物相互作用的系统评价
Psychosomatics. 2003 Jul-Aug;44(4):271-82. doi: 10.1176/appi.psy.44.4.271.
3
Panax ginseng: a systematic review of adverse effects and drug interactions.人参:不良反应与药物相互作用的系统评价
Drug Saf. 2002;25(5):323-44. doi: 10.2165/00002018-200225050-00003.
4
A case of ginseng-induced mania.
J Clin Psychopharmacol. 2001 Oct;21(5):535-7. doi: 10.1097/00004714-200110000-00015.
5
An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures.部分市售草药提取物和酊剂对人细胞色素P450 3A4抑制作用的体外评估
Phytomedicine. 2000 Jul;7(4):273-82. doi: 10.1016/S0944-7113(00)80044-6.
6
St. John's wort and schizophrenia.圣约翰草与精神分裂症。
CMAJ. 2000 Aug 8;163(3):262-3.
7
Inhibition of human cytochrome P450 enzymes by constituents of St. John's Wort, an herbal preparation used in the treatment of depression.用于治疗抑郁症的草药制剂圣约翰草的成分对人细胞色素P450酶的抑制作用。
J Pharmacol Exp Ther. 2000 Jul;294(1):88-95.
8
Psychiatric complications of Ma-huang.麻黄的精神科并发症。
Psychosomatics. 2000 Jan-Feb;41(1):58-62. doi: 10.1016/S0033-3182(00)71174-1.
9
Mania associated with St. John's wort.与圣约翰草相关的躁狂症。
Biol Psychiatry. 1999 Dec 15;46(12):1707-8. doi: 10.1016/s0006-3223(99)00233-4.
10
Alternative medicine: what the data say about common herbal therapies.
Geriatrics. 1999 Oct;54(10):33-8, 40, 43.

与圣约翰草和人参相关的躁狂和精神病。

Mania and Psychosis Associated with St. John's Wort and Ginseng.

作者信息

Joshi Kaustubh G, Faubion Matthew D

机构信息

Dr. Joshi is a staff forensic psychiatrist at Wilford Hall Medical Center (US Air Force).

出版信息

Psychiatry (Edgmont). 2005 Sep;2(9):56-61.

PMID:21120109
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2993537/
Abstract

The use of complimentary/alternative medicine has become popular as evidenced by grocery store aisles and "infomercials" devoted to herbal products. These products are often misconstrued as safe because of their natural origin. With an increase in the consumption of these products, physicians need to be aware of their potential adverse effects. There are several popular over-the-counter herbal products that can affect one's behavior, especially resulting in acute mania and/or psychosis. This article provides an overview of existing literature regarding the increased use of herbal agents, reviews several case reports describing a potential association between herbal products (St. John's Wort and ginseng) and the development of mania and psychosis, and discusses the limitations in determining the frequency of serious adverse effects due to herbal products.

摘要

从杂货店货架上摆满草药产品以及充斥着草药产品的“购物广告”可以看出,补充和替代医学的使用已变得十分普遍。由于这些产品源于天然,它们常常被误解为是安全的。随着这些产品消费量的增加,医生需要意识到它们潜在的不良反应。有几种常见的非处方草药产品会影响人的行为,尤其会导致急性躁狂和/或精神病。本文概述了有关草药制剂使用增加的现有文献,回顾了几例描述草药产品(圣约翰草和人参)与躁狂和精神病发生之间潜在关联的病例报告,并讨论了确定草药产品所致严重不良反应发生率方面的局限性。