Dysphagia. 2011 Mar;26(1):92-6. doi: 10.1007/s00455-010-9317-x.
Many people with Parkinson's disease (PD) experience dysphagia; however, the prevalence of dysphagia in people with PD is unknown. We studied a prevalent population of PD cases. All of those who consented to participate were assessed for anxiety, depression, cognitive function, and quality of life using standard rating scales. Anyone who answered "yes" to either one of the two questions: Do you have difficulty swallowing food/liquid or tablets? and Do you cough after eating/drinking? was considered to have dysphagia. Question 7 of the Unified Parkinson's Disease Rating Scale (UPDRS) was also used to identify dysphagia. Of 106 prevalent PD cases, 75 (38 males) patients consented to examination and assessment. The prevalence of dysphagia was 32.0% (n=24; 11 males). Using the response to UPDRS Question 7 as an indicator of the impact of swallowing problems on the patient, there were significant correlations with cognitive function, anxiety, depression, quality of life, and UPDRS-reported gait disturbance, postural instability and problems with falling. There was no correlation with disease duration, age, or gender. Almost one third of the participants reported dysphagia. There was a strong correlation between dysphagia and gross motor skills; patients reporting such problems should be screened for swallowing problems.
许多帕金森病（PD）患者存在吞咽困难；然而，PD 患者吞咽困难的患病率尚不清楚。我们研究了 PD 患者的流行人群。所有同意参与的人都使用标准评分量表评估焦虑、抑郁、认知功能和生活质量。任何对以下两个问题之一回答“是”的人：您是否有吞咽食物/液体或片剂的困难？和您进食/饮水后是否咳嗽？被认为存在吞咽困难。统一帕金森病评定量表（UPDRS）的问题 7 也用于识别吞咽困难。在 106 例流行 PD 病例中，有 75 名（38 名男性）患者同意接受检查和评估。吞咽困难的患病率为 32.0%（n=24；11 名男性）。使用 UPDRS 问题 7 的回答作为吞咽问题对患者影响的指标，与认知功能、焦虑、抑郁、生活质量以及 UPDRS 报告的步态障碍、姿势不稳和跌倒问题有显著相关性。与疾病持续时间、年龄或性别无关。近三分之一的参与者报告存在吞咽困难。吞咽困难与运动技能有很强的相关性；有此类问题的患者应进行吞咽问题筛查。
