Department of Voice, Speech and Hearing Disorders, Center for Clinical Neurosciences, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Department of Linguistics, Swallowing Research Lab, University of Potsdam, Potsdam, Germany.
Eur Arch Otorhinolaryngol. 2021 May;278(5):1661-1668. doi: 10.1007/s00405-020-06377-x. Epub 2020 Sep 26.
Dysphagia is common in patients with Parkinson's disease (PD) and often leads to pneumonia, malnutrition, and reduced quality of life. This study investigates the ability of the Eating Assessment Tool-10 (EAT-10), an established, easy self-administered screening tool, to detect aspiration in PD patients. This study aims to validate the ability of the EAT-10 to detect FEES-proven aspiration in patients with PD.
In a controlled prospective cross-sectional study, a total of 50 PD patients completed the EAT-10 and, subsequently, were examined by Flexible Endoscopic Evaluation of Swallowing (FEES) to determine the swallowing status. The results were rated through the Penetration-Aspiration Scale (PAS) and data were analyzed retrospectively.
PAS and EAT-10 did not correlate significantly. Selected items of the EAT-10 could not predict aspiration or residues. 19 (38%) out of 50 patients with either penetration or aspiration were not detected by the EAT-10. The diagnostic accuracy was established at only a sufficient level (AUC 0.65). An optimal cut-off value of ≥ 6 presented a sensitivity of 58% and specificity of 82%.
The EAT-10 is not suited for the detection of penetration and aspiration in PD patients. Therefore, it cannot be used as a screening method in this patient population. There is still a need for a valid, simple, and efficient screening tool to assist physicians in their daily diagnostics and to avoid clinical complications.
吞咽困难在帕金森病（PD）患者中很常见，常导致肺炎、营养不良和生活质量下降。本研究旨在评估已确立的简便自评工具——进食评估工具 10 项（EAT-10），检测 PD 患者误吸的能力。本研究旨在验证 EAT-10 检测 PD 患者经纤维内镜吞咽功能检查（FEES）证实的误吸的能力。
在一项对照前瞻性横断面研究中，共有 50 例 PD 患者完成了 EAT-10 测试，随后通过 FEES 检查确定吞咽状况。结果通过渗透-误吸量表（PAS）进行评分，并进行回顾性数据分析。
PAS 与 EAT-10 无显著相关性。EAT-10 的部分项目无法预测误吸或残留。EAT-10 无法检测到 50 例患者中有 19 例（38%）存在渗透或误吸。诊断准确性仅处于足够水平（AUC 0.65）。最佳截断值≥6 时，灵敏度为 58%，特异性为 82%。
EAT-10 不适合用于检测 PD 患者的渗透和误吸。因此，不能将其作为该患者人群的筛查方法。仍需要一种有效、简单、高效的筛查工具，以协助医生进行日常诊断，并避免临床并发症。
