Center on Aging Psychology, Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China.
Ageing Res Rev. 2011 Apr;10(2):285-96. doi: 10.1016/j.arr.2010.11.003. Epub 2010 Dec 2.
Cognitive training for persons with mild cognitive impairment (MCI) has become a hot topic. However to date it remains controversial whether persons with MCI can really benefit from cognitive intervention. We aim to further investigate this by using meta-analysis of seventeen clinical studies of cognitive intervention for MCI. The results demonstrate that after training, patients with MCI improve significantly both in overall cognition and overall self-ratings. Specifically, persons with MCI obtain moderate benefits in language, self-rated anxiety and functional ability, and receive mild benefits in episodic memory, semantic memory, executive functioning/working memory, visuo-spatial ability, attention/processing speed, MMSE, self-rated memory problem, quality of life, activities of daily life and self-rated depression. The results also suggest that persons with MCI benefit from the cognitive intervention in the follow-up data. The present meta-analysis demonstrates that cognitive intervention can be a potential efficient method to enhance cognitive and functional abilities in persons with MCI, although the improvements may be domain-specific.
认知训练对轻度认知障碍（MCI）患者来说已经成为一个热门话题。然而，到目前为止，MCI 患者是否真的能从认知干预中获益，仍然存在争议。我们旨在通过对 17 项认知干预 MCI 的临床研究进行荟萃分析来进一步研究这个问题。结果表明，经过训练，MCI 患者的整体认知和整体自我评估都有显著提高。具体来说，MCI 患者在语言、自我报告的焦虑和功能能力方面获得了中等程度的益处，在情景记忆、语义记忆、执行功能/工作记忆、视空间能力、注意力/处理速度、MMSE、自我报告的记忆问题、生活质量、日常生活活动和自我报告的抑郁方面获得了轻度的益处。结果还表明，MCI 患者在随访数据中也从认知干预中受益。本荟萃分析表明，认知干预可能是一种增强 MCI 患者认知和功能能力的潜在有效方法，尽管改善可能是特定于领域的。
