Department of Botany, Rheinisch-Westfälische Technische Hochschule Aachen University, Aachen 52056, Germany.
EMBO Rep. 2011 Jan;12(1):50-5. doi: 10.1038/embor.2010.186. Epub 2010 Dec 3.
Priming of defence genes for amplified response to secondary stress can be induced by application of the plant hormone salicylic acid or its synthetic analogue acibenzolar S-methyl. In this study, we show that treatment with acibenzolar S-methyl or pathogen infection of distal leaves induce chromatin modifications on defence gene promoters that are normally found on active genes, although the genes remain inactive. This is associated with an amplified gene response on challenge exposure to stress. Mutant analyses reveal a tight correlation between histone modification patterns and gene priming. The data suggest a histone memory for information storage in the plant stress response.
植物激素水杨酸或其合成类似物噻苯隆甲酯处理可诱导防御基因的预激活，以增强对二次胁迫的响应。本研究表明，噻苯隆甲酯处理或病原菌感染远端叶片会诱导防御基因启动子上的染色质修饰，这些修饰通常存在于活性基因上，尽管这些基因仍处于非活性状态。这与胁迫暴露时基因响应的增强有关。突变分析显示，组蛋白修饰模式与基因预激活之间存在紧密的相关性。这些数据表明，组蛋白在植物应激反应中具有信息存储的“记忆”功能。
