Moorman Claude T, Kirwan Tom, Share Jennifer, Vannabouathong Christopher
Department of Orthopaedic Surgery, Duke University School of Medicine, Durham, NC, USA.
Bruno and Ridgway Research Associates, Inc., Lawrenceville, NJ, USA.
Clin Med Insights Arthritis Musculoskelet Disord. 2017 Sep 20;10:1179544117732039. doi: 10.1177/1179544117732039. eCollection 2017.
Surgical interventions for knee osteoarthritis (OA) have markedly different procedure attributes and may have dramatic differences in patient desirability. A total of 323 patients with knee OA were included in a dual response, choice-based conjoint analysis to identify the relative preference of 9 different procedure attributes. A model was also developed to simulate how patients might respond if presented with the real-world knee OA procedures, based on conservative assumptions regarding their attributes. The "amount of cutting and removal of the existing bone" required for a procedure had the highest preference score, indicating that these patients considered it the most important attribute. More specifically, a procedure that requires the least amount of bone cutting or removal would be expected to be the most preferred surgical alternative. The model also suggested that patients who are younger and report the highest pain levels and greatest functional limitations would be more likely to opt for surgical intervention.
膝关节骨关节炎(OA)的手术干预具有明显不同的手术属性,在患者的接受度方面可能存在巨大差异。共有323例膝关节OA患者被纳入一项双响应、基于选择的联合分析,以确定9种不同手术属性的相对偏好。还开发了一个模型,基于对现实世界中膝关节OA手术属性的保守假设,模拟患者面对这些手术时可能的反应。手术所需的“现有骨质的切割和切除量”具有最高的偏好得分,表明这些患者认为这是最重要的属性。更具体地说,预计需要最少骨质切割或切除的手术将是最受青睐的手术选择。该模型还表明,年龄较小、报告疼痛程度最高且功能受限最严重的患者更有可能选择手术干预。