Institute of General Practice and Community Medicine, University of Oslo, Oslo, Norway.
Matern Child Nutr. 2011 Jan;7(1):92-9. doi: 10.1111/j.1740-8709.2009.00238.x.
A high prevalence of vitamin D deficiency has been reported in non-Western immigrants in Norway. Our objective was to test whether written information about how to improve vitamin D status could improve the vitamin D status in immigrants mothers attending child health clinics. In this cluster randomized controlled trial in eight child health clinics in Oslo, mothers aged 18-43 years with Pakistani, Turkish, or Somali background were included when their infants were 6 weeks old. The public health nurses gave the intervention group a brochure with information on how to improve vitamin D status, written in their native language. They were compared with a control group receiving usual care, consisting of oral information only. The principal outcome measure was increase in serum 25-hydroxyvitamin D [s-25(OH) D] in mothers 7 weeks later. Forty-four mothers completed the study. Mean baseline s-25(OH) D was 29.1 (14.8) nmol l(-1) in the intervention and 19.4 (9.2) in the control group. There was no significant increase in s-25(OH) D from baseline to follow-up in the intervention [6.3 (95%CI: -1.9, 14.4) nmol l(-1) )] or in the control group [2.9 (95% CI [confidence interval]: -1.2, 7.0) nmol l(-1) ]. When adjusting for baseline s-25(OH) D concentration the mean difference in increase between the intervention and control group was 1.4 (95% CI: -18.7, 21.4) nmol l(-1) (P = 0.87). Adjustment for ethnicity, season and mother's educational background did not alter the results. In sum, providing immigrant mothers with written information about how to improve their vitamin D status did not have an effect on the mothers' vitamin D status.
在挪威的非西方移民中，维生素 D 缺乏症的患病率很高。我们的目的是检验向在儿童保健诊所就诊的移民母亲提供有关如何改善维生素 D 状况的书面信息是否能改善其维生素 D 状况。在奥斯陆的八家儿童保健诊所进行的这项整群随机对照试验中，当婴儿 6 周大时，纳入了具有巴基斯坦、土耳其或索马里背景且年龄在 18-43 岁之间的母亲。公共卫生护士向干预组的母亲发放了一本用母语编写的小册子，其中介绍了改善维生素 D 状况的方法。然后将她们与接受仅口头信息的对照组进行比较。主要观察指标为 7 周后母亲血清 25-羟维生素 D[s-25(OH)D]的增加量。44 名母亲完成了这项研究。干预组的平均基线 s-25(OH)D 为 29.1(14.8)nmol/L，对照组为 19.4(9.2)nmol/L。干预组 s-25(OH)D 从基线到随访没有显著增加[6.3(95%置信区间：-1.9, 14.4)nmol/L]，对照组也没有显著增加[2.9(95%置信区间：-1.2, 7.0)nmol/L]。在校正基线 s-25(OH)D 浓度后，干预组与对照组的增加量差异平均为 1.4(95%置信区间：-18.7, 21.4)nmol/L(P=0.87)。校正种族、季节和母亲的教育背景后，结果并未改变。总之，向移民母亲提供有关如何改善其维生素 D 状况的书面信息对其维生素 D 状况没有影响。
