Münßinger Jana I, Halder Sebastian, Kleih Sonja C, Furdea Adrian, Raco Valerio, Hösle Adi, Kübler Andrea
Institute of Medical Psychology and Behavioral Neurobiology, University of Tübingen Tübingen, Germany.
Front Neurosci. 2010 Nov 22;4:182. doi: 10.3389/fnins.2010.00182. eCollection 2010.
Brain-computer interfaces (BCIs) enable paralyzed patients to communicate; however, up to date, no creative expression was possible. The current study investigated the accuracy and user-friendliness of P300-Brain Painting, a new BCI application developed to paint pictures using brain activity only. Two different versions of the P300-Brain Painting application were tested: A colored matrix tested by a group of ALS-patients (n = 3) and healthy participants (n = 10), and a black and white matrix tested by healthy participants (n = 10). The three ALS-patients achieved high accuracies; two of them reaching above 89% accuracy. In healthy subjects, a comparison between the P300-Brain Painting application (colored matrix) and the P300-Spelling application revealed significantly lower accuracy and P300 amplitudes for the P300-Brain Painting application. This drop in accuracy and P300 amplitudes was not found when comparing the P300-Spelling application to an adapted, black and white matrix of the P300-Brain Painting application. By employing a black and white matrix, the accuracy of the P300-Brain Painting application was significantly enhanced and reached the accuracy of the P300-Spelling application. ALS-patients greatly enjoyed P300-Brain Painting and were able to use the application with the same accuracy as healthy subjects. P300-Brain Painting enables paralyzed patients to express themselves creatively and to participate in the prolific society through exhibitions.
脑机接口（BCIs）能让瘫痪患者进行交流；然而，到目前为止，还无法实现创造性表达。当前的研究调查了P300脑绘这一新型BCI应用程序的准确性和用户友好性，该应用程序旨在仅利用大脑活动来绘制图片。对P300脑绘应用程序的两个不同版本进行了测试：一个彩色矩阵由一组肌萎缩侧索硬化症（ALS）患者（n = 3）和健康参与者（n = 10）进行测试，一个黑白矩阵由健康参与者（n = 10）进行测试。三名ALS患者取得了较高的准确率；其中两人准确率超过89%。在健康受试者中，对P300脑绘应用程序（彩色矩阵）和P300拼写应用程序进行比较发现，P300脑绘应用程序的准确率和P300波幅显著更低。当将P300拼写应用程序与P300脑绘应用程序改编后的黑白矩阵进行比较时，未发现准确率和P300波幅的这种下降。通过采用黑白矩阵，P300脑绘应用程序的准确率显著提高，并达到了P300拼写应用程序的准确率。ALS患者非常喜欢P300脑绘，并且能够以与健康受试者相同的准确率使用该应用程序。P300脑绘使瘫痪患者能够创造性地表达自己，并通过展览参与到丰富多彩的社会中。
