Stewart N P, de Vos A J, McHardy N, Standfast N F
Queensland Department of Primary Industries, Oonoonba Veterinary Laboratory, Townsville.
Trop Anim Health Prod. 1990 May;22(2):116-22. doi: 10.1007/BF02239836.
Attempts (some successful) were made to eliminate Theileria buffeli infections from 23 naturally or experimentally infected, splenectomised calves. The anti-theilerial hydroxynaphthoquinone derivative buparvaquone was used either alone or in combination with primaquine phosphate. After treatment the calves were monitored for infection for up to 26 weeks. Blood films were examined for piroplasms and serum antibody levels were measured using an immunofluorescence technique. Buparvaquone alone failed to eliminate infections. Infections were eliminated from 11 of 16 calves treated twice with buparvaquone and three or six times with primaquine phosphate. Theilerial parasites were not subsequently seen in these 11 calves nor were antibodies detected beyond the eighth week after treatment.
人们尝试（有些成功）从23头自然感染或实验感染且已切除脾脏的犊牛中清除水牛泰勒虫感染。抗泰勒虫羟基萘醌衍生物丁萘醌单独使用或与磷酸伯氨喹联合使用。治疗后，对犊牛进行长达26周的感染监测。检查血片是否有梨形虫，并使用免疫荧光技术测量血清抗体水平。单独使用丁萘醌未能清除感染。16头犊牛中，11头用丁萘醌治疗两次，并用磷酸伯氨喹治疗三次或六次后感染被清除。在这11头犊牛中，随后未再发现泰勒虫寄生虫，治疗后第八周后也未检测到抗体。
