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山羊锥虫病中的免疫抑制:急性刚果锥虫感染对炭疽芽孢疫苗抗体反应的影响。

Immunosuppression in caprine trypanosomiasis: effects of acute Trypanosoma congolense infection on antibody response to anthrax spore vaccine.

作者信息

Mwangi D M, Munyua W K, Nyaga P N

机构信息

Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, University of Nairobi, Kenya.

出版信息

Trop Anim Health Prod. 1990 May;22(2):95-100. doi: 10.1007/BF02239832.

Abstract

Trypanosoma congolense infected goats were vaccinated with Bacillus anthracis spore vaccine to determine the effect of such infection on the humoral immune response to the vaccine. The anti-anthrax antibody levels were severely depressed in infected goats. When trypanocidal therapy was administered to T. congolense infected goats 14 days after infection they developed antibody levels against Bacillus anthracis similar to uninfected controls.

摘要

用炭疽芽孢杆菌疫苗对感染刚果锥虫的山羊进行接种,以确定这种感染对疫苗体液免疫反应的影响。感染山羊体内的抗炭疽抗体水平严重降低。在感染刚果锥虫的山羊感染14天后进行杀锥虫治疗,它们产生的抗炭疽芽孢杆菌抗体水平与未感染的对照组相似。

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