Warren Alpert School of Medicine, Brown University, Providence, RI, USA.
Arch Womens Ment Health. 2011 Feb;14(1):55-65. doi: 10.1007/s00737-010-0195-x. Epub 2010 Dec 11.
This study assessed the initial feasibility, acceptability, and efficacy of an intervention aimed at reducing depression and posttraumatic stress disorder (PTSD) in a sample of low-income pregnant women with recent intimate partner violence (IPV). Fifty-four women were randomly assigned to the intervention or control group. The intervention consisted of four sessions during pregnancy and one "booster" session within 2 weeks of delivery. Based on principles of Interpersonal Psychotherapy, the intervention was designed to help participants improve their interpersonal relationships, including their social support networks, and master their role transition to motherhood. Assessments were administered at four time points (intake, 5-6 weeks post-intake, 2 weeks postpartum, 3 months postpartum) to assess for depression, PTSD, and IPV. The intervention did not significantly reduce the likelihood of a major depressive episode, PTSD, or IPV during pregnancy or up to 3-month postpartum. However, we found moderate effects for the intervention in reducing symptoms of PTSD and depression during pregnancy and a large effect for PTSD symptoms from pregnancy up to 3 months postpartum. This study suggests some initial support for our intervention. Larger randomized trials are needed to further examine the intervention both during and after pregnancy.
本研究评估了一项旨在减少低收入孕妇近期亲密伴侣暴力（IPV）后抑郁和创伤后应激障碍（PTSD）的干预措施的初步可行性、可接受性和疗效。54 名女性被随机分配到干预组或对照组。该干预措施包括怀孕期间的四个疗程和分娩后 2 周内的一次“强化”疗程。基于人际心理治疗原则，该干预旨在帮助参与者改善人际关系，包括他们的社会支持网络，并掌握他们作为母亲的角色转变。在四个时间点（入组时、入组后 5-6 周、产后 2 周、产后 3 个月）进行评估，以评估抑郁、PTSD 和 IPV。在怀孕期间或产后 3 个月内，该干预措施并未显著降低重度抑郁发作、PTSD 或 IPV 的可能性。然而，我们发现该干预措施在怀孕期间减轻 PTSD 和抑郁症状方面具有中等效果，在从怀孕到产后 3 个月的时间内对 PTSD 症状具有较大效果。本研究为我们的干预措施提供了一些初步支持。需要更大规模的随机试验来进一步研究该干预措施在怀孕期间和之后的效果。
